Traumatic spinal cord injury (SCI) is a devastating neurological condition that results in a
loss of motor and sensory function. Although extensive research to develop treatments for …

Degenerative cervical myelopathy (DCM) is the leading cause of spinal cord dysfunction in
adults worldwide. DCM encompasses various acquired (age-related) and congenital …

Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …

Although lesion size is widely considered to be the most reliable predictor of outcome after
CNS injury, lesions of comparable size can produce vastly different magnitudes of functional …

Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

Pattern recognition receptors (PRRs) are part of the innate immune response and were
originally discovered for their role in recognizing pathogens by ligating specific pathogen …

Biochemical and neuropathological studies of brains from individuals with Alzheimer
disease (AD) provide clear evidence for an activation of inflammatory pathways, and long …

Glial cell types were classified less than 100 years ago by del Rio-Hortega. For instance, he
correctly surmised that microglia in pathologic central nervous system (CNS) were …

Cervical spondylotic myelopathy (CSM) is a common disorder involving chronic progressive
compression of the cervical spinal cord due to degenerative disc disease, spondylosis, or …

The zebrafish regenerates its brain after injury and hence is a useful model organism to
study the mechanisms enabling regenerative neurogenesis, which is poorly manifested in …