Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that drives the
generation of myeloid cell subsets including neutrophils, monocytes, macrophages, and …

A number of noteworthy technology advances in DNA vaccines research and development
over the past few years have led to the resurgence of this field as a viable vaccine modality …

The development and widespread use of vaccines against infectious agents have been a
great triumph of medical science. One reason for the success of currently available vaccines …

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is an important hematopoietic
growth factor and immune modulator. GM-CSF also has profound effects on the functional …

A DNA-based vaccine containing human immunodeficiency virus type 1 (HIV-1) env and rev
genes was tested for safety and host immune response in 15 asymptomatic HIV-infected …

Publisher Summary Although interleukin-12 (IL-12) has been discovered only relatively
recently, a remarkable level of knowledge has been obtained for this cytokine, and many …

Purpose: Clinical responses with programmed death (PD-1) receptor–directed antibodies
occur in about 20% of patients with advanced head and neck squamous cell cancer …

ABSTRACT DNA vaccination elicits humoral and cellular immune responses and has been
shown to confer protection against several viral, bacterial, and parasitic pathogens. Here we …

An attenuated strain of S. typhimurium has been used as a vehicle for oral genetic
immunization. Eukaryotic expression vectors containing truncated genes of ActA and …

Summary Background Interleukin-12 (IL-12) is a macrophage-derived cytokine that
modulates T lymphocyte responses and has the capacity to suppress allergic and …