Metabarcoding has been used in a range of ecological applications such as taxonomic
assignment, dietary analysis and the analysis of environmental DNA. However, after a …

Certified RNA reference materials are indispensable for assessing the reliability of RNA
sequencing to detect intrinsically small biological differences in clinical settings, such as …

Sustained smouldering, or low-grade activation, of myeloid cells is a common hallmark of
several chronic neurological diseases, including multiple sclerosis. Distinct metabolic and …

Abstract RNA-sequencing (RNA-seq) is a relatively new technology that lacks
standardisation. RNA-seq can be used for Differential Gene Expression (DGE) analysis …

The human innate immune system responds to both pathogen and commensal bacteria at
the molecular level using bacterial peptidoglycan (PG) recognition elements. Traditionally …

Zika virus (ZIKV) can infect human developing brain (HDB) progenitors resulting in epidemic
microcephaly, whereas analogous cellular tropism offers treatment potential for the adult …

Rett Syndrome (RTT) is a neurological disorder mainly associated with mutations in the X-
linked gene coding for the methyl-CpG binding protein 2 (MECP2). To assist in studying …

Aims Cardiac involvement is common in patients hospitalized with COVID-19 and correlates
with an adverse disease trajectory. While cardiac injury has been attributed to direct viral …

Motivation RNA interference, a highly conserved regulatory mechanism, is mediated via
small RNAs (sRNA). Recent technical advances enabled the analysis of larger, complex …

Background RNA-seq is poised to play a major role in the management of kidney transplant
patients. Rigorous definition of housekeeping genes (HKG) is essential for further progress …