Sympathetic nervous system overactivity and its role in the development of cardiovascular disease

SC Malpas - Physiological reviews, 2010 - journals.physiology.org
This review examines how the sympathetic nervous system plays a major role in the
regulation of cardiovascular function over multiple time scales. This is achieved through …

Aldosterone in congestive heart failure

KT Weber - New England Journal of Medicine, 2001 - Mass Medical Soc
The potent mineralocorticoid aldosterone has a multifaceted role in the pathogenesis of
congestive heart failure. In addition to its contribution to salt and water retention, it also …

[HTML][HTML] Exercise training-induced modification in autonomic nervous system: An update for cardiac patients

F Besnier, M Labrunee, A Pathak… - Annals of physical and …, 2017 - Elsevier
Patients with cardiovascular disease show autonomic dysfunction, including sympathetic
activation and vagal withdrawal, which leads to fatal events. This review aims to place …

Central mechanisms underlying short‐and long‐term regulation of the cardiovascular system

RAL Dampney, MJ Coleman… - Clinical and …, 2002 - Wiley Online Library
Sympathetic vasomotor nerves play a major role in determining the level of arterial blood
pressure and the distribution of cardiac output. The present review will discuss briefly the …

[图书][B] Brenner & Rector's the kidney

K Skorecki, GM Chertow, PA Marsden, MW Taal… - 2016 - doctorlib.info
The volume of extracellular fluid (ECF) is maintained within narrow limits in normal human
subjects, despite day-to-day variations in dietary intake of salt and water over a wide range …

Translational neurocardiology: preclinical models and cardioneural integrative aspects

JL Ardell, MC Andresen, JA Armour… - The Journal of …, 2016 - Wiley Online Library
Neuronal elements distributed throughout the cardiac nervous system, from the level of the
insular cortex to the intrinsic cardiac nervous system, are in constant communication with …

Effects of intravenous brain natriuretic peptide on regional sympathetic activity in patients with chronic heart failure as compared with healthy control subjects

HP Brunner-La Rocca, DM Kaye, RL Woods… - Journal of the American …, 2001 - jacc.org
OBJECTIVES We sought to assess the effects of brain natriuretic peptide (BNP) on systemic
and regional sympathetic nervous activity (SNA) in both patients with congestive heart …

Cardiac afferents play the dominant role in renal nerve inhibition elicited by volume expansion in the rabbit

E Badoer, V Moguilevski… - American Journal of …, 1998 - journals.physiology.org
In the rabbit, vagotomy combined with arterial baroreceptor denervation abolishes the renal
sympathoinhibition elicited by volume expansion. However, the effect of removing …

[HTML][HTML] The origin of sympathetic outflow in heart failure: the roles of angiotensin II and nitric oxide

IH Zucker, HD Schultz, YF Li, Y Wang, W Wang… - Progress in biophysics …, 2004 - Elsevier
The regulation of sympathetic nerve activity in chronic heart failure (CHF) has been an area
of renewed investigation. Understanding the central mechanisms that are responsible for …

Reverse re-modelling chronic heart failure by reinstating heart rate variability

J Shanks, Y Abukar, NA Lever, M Pachen… - Basic Research in …, 2022 - Springer
Heart rate variability (HRV) is a crucial indicator of cardiovascular health. Low HRV is
correlated with disease severity and mortality in heart failure. Heart rate increases and …