Pathological features and prognostication in colorectal cancer

K Chen, G Collins, H Wang, JWT Toh - Current Oncology, 2021 - mdpi.com
The prognostication of colorectal cancer (CRC) has traditionally relied on staging as defined
by the Union for International Cancer Control (UICC) and American Joint Committee on …

The role of heavy metals in the development of colorectal cancer

Y Li, J Lou, S Hong, D Hou, Y Lv, Z Guo, K Wang, Y Xu… - BMC cancer, 2023 - Springer
Objective To investigate the relationship among 18 heavy metals, microsatellite instability
(MSI) status, ERCC1, XRCC1 (rs25487), BRAF V600E and 5 tumor markers and their role in …

Current perspectives on the importance of pathological features in prognostication and guidance of adjuvant chemotherapy in colon cancer

K Chen, H Wang, G Collins, E Hollands, IYJ Law… - Current …, 2022 - mdpi.com
There is not a clear consensus on which pathological features and biomarkers are important
in guiding prognosis and adjuvant therapy in colon cancer. The Pathology in Colon Cancer …

Association between colorectal cancer and Fusobacterium nucleatum and Bacteroides fragilis bacteria in Iranian patients: a preliminary study

A Shariati, S Razavi, E Ghaznavi-Rad… - Infectious agents and …, 2021 - Springer
Background and aim Recent studies have proposed that commensal bacteria might be
involved in the development and progression of gastrointestinal disorders such as colorectal …

Identification of antisense and sense RNAs of intracrine fibroblast growth factor components as novel biomarkers in colorectal cancer and in silico studies for drug and …

L Rejali, E Nazemalhosseini-Mojarad, L Valle… - Environmental …, 2023 - Elsevier
Introduction Colorectal cancer (CRC) is one of the most malignant tumors and in which
various efforts for screening is inconclusive. The intracrine FGF panel, the non-tyrosine …

[HTML][HTML] Different oncological features of colorectal cancer codon-specific KRAS mutations: Not codon 13 but codon 12 have prognostic value

HM Ahn, DW Kim, HJ Oh, HK Kim, HS Lee… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Approximately 40% of colorectal cancer (CRC) cases are linked to Kirsten
rat sarcoma viral oncogene homolog (KRAS) mutations. KRAS mutations are associated …

Exploring the Relationship Between KRAS, NRAS, and BRAF Mutations and Clinical Characteristics in Iranian Colorectal Cancer Patients

Z Mosaferi, M Pirestani, E Arefian, G Gojani… - Journal of …, 2024 - Springer
Background Patients with colorectal cancer can benefit from anti-EGFR (epidermal growth
factor receptor) therapy. However, this therapy is not effective for treating colorectal cancers …

KRAS, NRAS, BRAF, and PIK3CA mutation rates, clinicopathological association, and their prognostic value in Iranian colorectal cancer patients

Z Mirzapoor Abbasabadi, D Hamedi Asl… - Journal of clinical …, 2023 - Wiley Online Library
Abstract Aim Mutations in KRAS, NRAS, BRAF, and PIK3CA genes are critical factors in
clinical evaluation of colorectal cancer (CRC) development and progression. In Iran …

Mutation status and prognostic value of KRAS and BRAF in Southeast Iranian colorectal cancer patients: first report from Southeast of Iran

A Yari, A Samoudi, A Afzali, ZM Karam… - Journal of …, 2021 - Springer
Abstract Main Purpose This study aimed to determine any association of KRAS and BRAF
mutations in colorectal cancer with clinicopathological features and overall survival (OS) of …

Can hypoxia-inducible factor-1α overexpression discriminate human colorectal cancers with different microsatellite instability?

Z Arabsorkhi, H Sadeghi, E Gharib, L Rejali… - Genes & Genetic …, 2021 - jstage.jst.go.jp
Clinicopathological features of high-frequency microsatellite instability (MSI-H) colorectal
cancers (CRCs) are different from low-frequency MSI (MSI-L) and microsatellite stable …