Cancer metastasis is a major cause of mortality from several tumors, including those of the
breast, prostate, and the thyroid gland. Since bone tissue is one of the most common sites of …

Different types of cytokines, growth factors, or hormones present within the tumor
microenvironment that can activate the JAK-STAT signaling pathway by binding to their …

Bladder cancer (BLCA) is more common in men but more aggressive in women. Sex-based
differences in cancer biology are commonly studied using a murine model with BLCA …

Abstract Background Prostatic cancer (PCa) is one of the most common malignant tumors in
men worldwide. Emerging evidence indicates significance of hypoxia and immunity in PCa …

Melanoma is a highly malignant skin tumor with poor prognosis. Circadian rhythm is closely
related to melanoma pathogenesis. This study aimed to identify key circadian rhythm genes …

Fatty acid-binding protein 5 (FABP5) and androgen receptor (AR) are critical promoters of
prostate cancer. In the present study, the effects of knocking out the FABP5 or AR genes on …

Background Anaplastic thyroid carcinoma (ATC) was a rare and extremely malignant
endocrine cancer. Recently, dysregulation of circadian rhythm genes was demonstrated to …

Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer and
poses a treatment challenge due to high recurrence risk. Consequently, there is an urgent …

Breast cancer represents a critical global health issue, accounting for a substantial portion of
cancer-related deaths worldwide. Metastasis, the spread of cancer cells to distant organs, is …

Abstract Phosphoinositide-3-kinase-γ (PI3Kγ) is implicated as a target to repolarize tumour-
associated macrophages and promote antitumour immune responses in solid cancers …