Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

An urgent need for early detection and diagnosis of diseases continuously pushes the
advancements of imaging modalities and contrast agents. Current challenges remain for fast …

Acute inflammation is essential for initiating and coordinating the body's response to injuries
and infections. However, in acute inflammatory diseases, inflammation is not resolved but …

The widespread development of nanocarriers to deliver chemotherapeutics to specific tumor
sites has been motivated by the lack of selective targeting during chemotherapy inducing …

Recent progress in RNA biology has broadened the scope of therapeutic targets of RNA
drugs for cancer therapy. However, RNA drugs, typically small interfering RNAs (siRNAs) …

Targeted nano-drug delivery systems conjugated with specific ligands to target selective cell-
surface receptors or transporters could enhance the efficacy of drug delivery and therapy …

Targeted delivery of therapeutic and imaging agents in the vascular compartment represents
a significant hurdle in using nanomedicine for treating hemorrhage, thrombosis, and …

Endothelial cells represent the first biological barrier for compounds, including
nanoparticles, administered via the intravascular route. In the case of ischemic stroke and …

Despite considerable progress in the design of multifunctionalized nanoparticles (NPs) that
selectively target specific cell types, their systemic application often results in unwanted liver …

Nanotechnology has the potential to increase the selectivity and potency of chemical,
physical, and biological approaches for eliciting cancer cell death while minimizing …