The prefrontal cortex (PFC) serves as the chief executive officer of the brain, controlling the
highest level cognitive and emotional processes. Its local circuits among glutamatergic …

The hippocampus-prefrontal cortex (HPC-PFC) pathway plays a fundamental role in
executive and emotional functions. Neurophysiological studies have begun to unveil the …

Synaptic pruning during adolescence is important for appropriate neurodevelopment and
synaptic plasticity. Aberrant synaptic pruning may underlie a variety of brain disorders such …

Adolescence poses as both a transitional period in neurodevelopment and lifestyle
practices. In particular, the developmental trajectory of the prefrontal cortex (PFC), a critical …

Repetitive transcranial magnetic stimulation (rTMS) is an effective clinical intervention for
various neuropsychiatric diseases. However, it is still unclear whether rTMS has an effect on …

The molecular pathways underlying the induction and maintenance of long-term synaptic
plasticity have been extensively investigated revealing various mechanisms by which …

Among various hippocampal rhythms, including sharp-wave ripples, gamma, and theta,
theta rhythm is crucial for cognitive processing, particularly learning and memory. Theta …

NMDA receptors (NMDARs) play a critical role in excitatory synaptic transmission, plasticity
and in several forms of learning and memory. In addition, NMDAR dysfunction is believed to …

Cannabidiol (CBD) is a promising neurological agent with potential beneficial effects on
memory and cognitive function. The combination of CBD and topiramate in the treatment of …

Contextual memory driven by abused drugs such as opiates has a central role in
maintenance and relapse of drug-taking behaviors. Although dopamine (DA) signaling …