In the last two decades, solid-state nuclear magnetic resonance (ssNMR) spectroscopy has
transformed from a spectroscopic technique investigating small molecules and industrial …

Infectious proteins or prions are a remarkable class of pathogens, where pathogenicity and
infectious state correspond to conformational transition of a protein fold. The conformational …

NMR is a noninvasive, molecular-level spectroscopic technique widely used for chemical
characterization. However, it lacks the sensitivity to probe the small number of spins at …

Porous organic frameworks that can dynamically expand their voids to guest uptake remain
formidable to design. The challenge comes from finding the balance between rigidity and …

Solution NMR is a key tool to study intrinsically disordered proteins (IDPs), whose
importance for biological function is widely accepted. However, disordered proteins are not …

Solution-state NMR relaxation experiments are the cornerstone to study internal protein
dynamics at an atomic resolution on time scales that are faster than the overall rotational …

Slow timescale dynamics in proteins are essential for a variety of biological functions
spanning ligand binding, enzymatic catalysis, protein folding and misfolding regulations, as …

Post-translationally modified (PTM) amyloid-β (Aβ) species can play an important role in
modulating Alzheimer's disease pathology. These relatively less populated modifications …

We demonstrate the feasibility of deuterium solid-state NMR off-resonance rotating frame
relaxation measurements for studies of slow motions in biomolecular solids. The pulse …

We describe a 2 H based MAS nuclear magnetic resonance (NMR) method to obtain site-
specific molecular dynamics of biomolecules. The method utilizes the use of deuterium …