Targeting the Hippo/YAP1 signaling pathway in hepatocellular carcinoma: From mechanisms to therapeutic drugs
S Li, L Hao, N Li, X Hu, H Yan… - … Journal of Oncology, 2024 - spandidos-publications.com
The Hippo signaling pathway plays a pivotal role in regulating cell growth and organ size. Its
regulatory effects on hepatocellular carcinoma (HCC) encompass diverse aspects, including …
regulatory effects on hepatocellular carcinoma (HCC) encompass diverse aspects, including …
[HTML][HTML] Molecular Mechanisms of Fibrosis in Cholestatic Liver Diseases and Regenerative Medicine-Based Therapies
WL Wang, H Lian, Y Liang, Y Ye, PKH Tam, Y Chen - Cells, 2024 - mdpi.com
The aim of this review is to explore the potential of new regenerative medicine approaches
in the treatment of cholestatic liver fibrosis. Cholestatic liver diseases, such as primary biliary …
in the treatment of cholestatic liver fibrosis. Cholestatic liver diseases, such as primary biliary …
[HTML][HTML] CRKL Enhances YAP Signaling through Binding and JNK/JUN Pathway Activation in Liver Cancer
MC Wesener, SME Weiler, M Bissinger… - International journal of …, 2024 - mdpi.com
The Hippo pathway transducers yes-associated protein (YAP) and WW-domain containing
transcription regulator 1 (WWTR1/TAZ) are key regulators of liver tumorigenesis, promoting …
transcription regulator 1 (WWTR1/TAZ) are key regulators of liver tumorigenesis, promoting …
Interplay between YAP/TAZ and metabolic dysfunction-associated steatotic liver disease progression
NY Lee, MG Choi, EJ Lee, JH Koo - Archives of Pharmacal Research, 2024 - Springer
Metabolic dysfunction-associated steatotic liver disease (MASLD) is becoming an
increasingly pressing global health challenge, with increasing mortality rates showing an …
increasingly pressing global health challenge, with increasing mortality rates showing an …