Unlocking therapeutic potential: exploring cross-talk among emerging nuclear receptors to combat metabolic dysfunction in steatotic liver disease
Nuclear receptors (NRs) regulate cellular processes and serve as key targets in treating
metabolic dysfunction-associated steatotic liver disease (MASLD) and steatohepatitis …
metabolic dysfunction-associated steatotic liver disease (MASLD) and steatohepatitis …
[HTML][HTML] The emerging role of gut hormones
H Cho, J Lim - Molecules and Cells, 2024 - Elsevier
The gut is traditionally recognized as the central organ for the digestion and absorption of
nutrients, however it also functions as a significant endocrine organ, secreting a variety of …
nutrients, however it also functions as a significant endocrine organ, secreting a variety of …
Colitis induces sex-specific intestinal transcriptomic responses in mice
L Hases, M Birgersson, R Indukuri, A Archer… - International Journal of …, 2022 - mdpi.com
There are significant sex differences in colorectal cancer (CRC), including in incidence,
onset, and molecular characteristics. Further, while inflammatory bowel disease (IBD) is a …
onset, and molecular characteristics. Further, while inflammatory bowel disease (IBD) is a …
Pictolysin-III, a Hemorrhagic Type-III Metalloproteinase Isolated from Bothrops pictus (Serpentes: Viperidae) Venom, Reduces Mitochondrial Respiration and Induces …
From the venom of the Bothrops pictus snake, an endemic species from Peru, we recently
have described toxins that inhibited platelet aggregation and cancer cell migration. In this …
have described toxins that inhibited platelet aggregation and cancer cell migration. In this …
Liver receptor homolog-1: structures, related diseases, and drug discovery
T Wu, Z Lu, H Yu, X Wu, Y Liu, Y Xu - Acta Pharmacologica Sinica, 2024 - nature.com
Abstract Liver receptor homolog-1 (LRH-1), a member of the nuclear receptor superfamily, is
a ligand-regulated transcription factor that plays crucial roles in metabolism, development …
a ligand-regulated transcription factor that plays crucial roles in metabolism, development …
Immune Modulations by Glucocorticoids: From Molecular Biology to Clinical Research
M JM Schaaf, OC Meijer - Cells, 2022 - mdpi.com
Due to their potent anti-inflammatory and immune-suppressive actions, glucocorticoids have
been used in the treatment of inflammatory and autoimmune disease for more than 70 years …
been used in the treatment of inflammatory and autoimmune disease for more than 70 years …
[PDF][PDF] M., & Mei er, OC (2022)
M Schaaf - … b glucocorticoids: from molecular biolog to … - scholarlypublications …
Due to their potent anti-inflammatory and immune-suppressive actions, glucocorticoids have
been used in the treatment of inflammatory and autoimmune disease for more than 70 years …
been used in the treatment of inflammatory and autoimmune disease for more than 70 years …