[HTML][HTML] Decoding early psychoses: Unraveling stable microstructural features associated with psychopathology across independent cohorts

HR Wang, ZQ Liu, H Nakua, CE Hegarty, MB Thies… - Biological …, 2025 - Elsevier
Background Patients with early psychosis (EP)(within 3 years after psychosis onset) show
significant variability, which makes predicting outcomes challenging. Currently, little …

Rich-club connectivity and structural connectome organization in youth at clinical high-risk for psychosis and individuals with early illness schizophrenia

JPY Hua, J Cummings, BJ Roach, SL Fryer… - Schizophrenia …, 2023 - Elsevier
Brain dysconnectivity has been posited as a biological marker of schizophrenia. Emerging
schizophrenia connectome research has focused on rich-club organization, a tendency for …

Brain Age Gap in Early Illness Schizophrenia and the Clinical High-Risk Syndrome: Associations With Experiential Negative Symptoms and Conversion to Psychosis

JPY Hua, SV Abram, RL Loewy, B Stuart… - Schizophrenia …, 2024 - academic.oup.com
Abstract Background and Hypothesis Brain development/aging is not uniform across
individuals, spawning efforts to characterize brain age from a biological perspective to …

[HTML][HTML] Adjustment of Regional Cortical Thickness Measures for Global Cortical Thickness Obscures Deficits Across the Schizophrenia Spectrum: A Cautionary Note …

JPY Hua, SL Fryer, B Stuart, RL Loewy… - Biological Psychiatry …, 2024 - Elsevier
Recent neuroimaging studies and publicly-disseminated analytic tools advocate that
regional morphometric analyses covary for global thickness. We empirically demonstrate …

Cortical and subcortical brain morphometry abnormalities in youth at clinical high-risk for psychosis and individuals with early illness schizophrenia

JPY Hua, RL Loewy, B Stuart, SL Fryer… - Psychiatry Research …, 2023 - Elsevier
Neuroimaging studies have documented morphometric brain abnormalities in
schizophrenia, but less is known about them in individuals at clinical high-risk for psychosis …