Gut microbiota in colorectal cancer: mechanisms of action and clinical applications
Colorectal cancer (CRC) accounts for about 10% of all new cancer cases globally. Located
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …
The intestinal microbiota fuelling metabolic inflammation
Low-grade inflammation is the hallmark of metabolic disorders such as obesity, type 2
diabetes and nonalcoholic fatty liver disease. Emerging evidence indicates that these …
diabetes and nonalcoholic fatty liver disease. Emerging evidence indicates that these …
Metabolism and metabolic disorders and the microbiome: the intestinal microbiota associated with obesity, lipid metabolism, and metabolic health—pathophysiology …
J Aron-Wisnewsky, MV Warmbrunn, M Nieuwdorp… - Gastroenterology, 2021 - Elsevier
Changes in the intestinal microbiome have been associated with obesity and type 2
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …
Leaky gut: mechanisms, measurement and clinical implications in humans
M Camilleri - Gut, 2019 - gut.bmj.com
The objectives of this review on 'leaky gut'for clinicians are to discuss the components of the
intestinal barrier, the diverse measurements of intestinal permeability, their perturbation in …
intestinal barrier, the diverse measurements of intestinal permeability, their perturbation in …
[HTML][HTML] Establishing or exaggerating causality for the gut microbiome: lessons from human microbiota-associated rodents
Human diseases are increasingly linked with an altered or" dysbiotic" gut microbiota, but
whether such changes are causal, consequential, or bystanders to disease is, for the most …
whether such changes are causal, consequential, or bystanders to disease is, for the most …
[HTML][HTML] Brain-gut axis dysfunction in the pathogenesis of traumatic brain injury
M Hanscom, DJ Loane… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
Traumatic brain injury (TBI) is a chronic and progressive disease, and management requires
an understanding of both the primary neurological injury and the secondary sequelae that …
an understanding of both the primary neurological injury and the secondary sequelae that …
[HTML][HTML] Human microbiome: an academic update on human body site specific surveillance and its possible role
E Dekaboruah, MV Suryavanshi, D Chettri… - Archives of …, 2020 - Springer
Human body is inhabited by vast number of microorganisms which form a complex
ecological community and influence the human physiology, in the aspect of both health and …
ecological community and influence the human physiology, in the aspect of both health and …
[HTML][HTML] Fecal microbiota transplantation for the improvement of metabolism in obesity: The FMT-TRIM double-blind placebo-controlled pilot trial
EW Yu, L Gao, P Stastka, MC Cheney… - PLoS …, 2020 - journals.plos.org
Background There is intense interest about whether modulating gut microbiota can impact
systemic metabolism. We investigated the safety of weekly oral fecal microbiota …
systemic metabolism. We investigated the safety of weekly oral fecal microbiota …
Bacterial SNPs in the human gut microbiome associate with host BMI
Genome-wide association studies (GWASs) have provided numerous associations between
human single-nucleotide polymorphisms (SNPs) and health traits. Likewise, metagenome …
human single-nucleotide polymorphisms (SNPs) and health traits. Likewise, metagenome …
[HTML][HTML] The role of probiotics and prebiotics in the prevention and treatment of obesity
Obesity is a global pandemic complex to treat due to its multifactorial pathogenesis—an
unhealthy lifestyle, neuronal and hormonal mechanisms, and genetic and epigenetic factors …
unhealthy lifestyle, neuronal and hormonal mechanisms, and genetic and epigenetic factors …