The role of nectins in different types of cell–cell adhesion

Y Rikitake, K Mandai, Y Takai - Journal of cell science, 2012 - journals.biologists.com
Mammalian tissues and organs are composed of different types of cells that adhere to each
other homotypically (ie interactions between cells of the same cell type) or heterotypically (ie …

Nectins and nectin-like molecules in development and disease

K Mandai, Y Rikitake, M Mori, Y Takai - Current topics in developmental …, 2015 - Elsevier
Nectins and nectin-like molecules (Necls)/Cadms are Ca 2+-independent immunoglobulin
superfamily cell adhesion molecules, expressed in most cell types. Nectins mediate not only …

Claudins and JAM-A coordinately regulate tight junction formation and epithelial polarity

T Otani, TP Nguyen, S Tokuda, K Sugihara… - Journal of Cell …, 2019 - rupress.org
Tight junctions (TJs) establish the epithelial barrier and are thought to form a membrane
fence to regulate epithelial polarity, although the roles of TJs in epithelial polarity remain …

Dynamics and regulation of epithelial adherens junctions: recent discoveries and controversies

AI Ivanov, NG Naydenov - International review of cell and molecular …, 2013 - Elsevier
Adherens junctions (AJs) are evolutionarily conserved plasma-membrane structures that
mediate cell–cell adhesions in multicellular organisms. They are organized by several types …

FRMD6 has tumor suppressor functions in prostate cancer

J Haldrup, SH Strand, C Cieza-Borrella, ME Jakobsson… - Oncogene, 2021 - nature.com
Available tools for prostate cancer (PC) prognosis are suboptimal but may be improved by
better knowledge about genes driving tumor aggressiveness. Here, we identified FRMD6 …

[HTML][HTML] Optimal myelin elongation relies on YAP activation by axonal growth and inhibition by Crb3/Hippo pathway

RN Fernando, L Cotter, C Perrin-Tricaud… - Nature …, 2016 - nature.com
Fast nerve conduction relies on successive myelin segments that electrically isolate axons.
Segment geometry—diameter and length—is critical for the optimization of nerve conduction …

[HTML][HTML] Differential expression of a classic cadherin directs tissue-level contractile asymmetry during neural tube closure

H Hashimoto, E Munro - Developmental cell, 2019 - cell.com
Embryos control force generation at tissue boundaries, but how they do so remains poorly
understood. Here we show how tissue-specific expression of the type II cadherin …

The expanding family of FERM proteins

S Moleirinho, A Tilston-Lunel, L Angus… - Biochemical …, 2013 - portlandpress.com
Our understanding of the FERM (4.1/ezrin/radixin/moesin) protein family has been rapidly
expanding in the last few years, with the result that many new physiological functions have …

Nectin spot: a novel type of nectin-mediated cell adhesion apparatus

K Mizutani, Y Takai - Biochemical Journal, 2016 - portlandpress.com
Nectins are Ca2+-independent immunoglobulin (Ig) superfamily cell adhesion molecules
constituting a family with four members, all of which have three Ig-like loops at their …

[HTML][HTML] PLEKHA7 recruits PDZD11 to adherens junctions to stabilize nectins

D Guerrera, J Shah, E Vasileva, S Sluysmans… - Journal of Biological …, 2016 - ASBMB
PLEKHA7 is a junctional protein implicated in stabilization of the cadherin protein complex,
hypertension, cardiac contractility, glaucoma, microRNA processing, and susceptibility to …