Modulation of immune responses by particle size and shape

MV Baranov, M Kumar, S Sacanna… - Frontiers in …, 2021 - frontiersin.org
The immune system has to cope with a wide range of irregularly shaped pathogens that can
actively move (eg, by flagella) and also dynamically remodel their shape (eg, transition from …

The fungal cell wall: structure, biosynthesis, and function

NAR Gow, JP Latge, CA Munro - Microbiology spectrum, 2017 - Am Soc Microbiol
The molecular composition of the cell wall is critical for the biology and ecology of each
fungal species. Fungal walls are composed of matrix components that are embedded and …

Extracellular Vesicles from Cryptococcus neoformans Modulate Macrophage Functions

DL Oliveira, CG Freire-de-Lima… - Infection and …, 2010 - Am Soc Microbiol
Cryptococcus neoformans and distantly related fungal species release extracellular vesicles
that traverse the cell wall and contain a varied assortment of components, some of which …

Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species

AM Andrianaki, I Kyrmizi, K Thanopoulou… - Nature …, 2018 - nature.com
Mucormycosis is a life-threatening respiratory fungal infection predominantly caused by
Rhizopus species. Mucormycosis has incompletely understood pathogenesis, particularly …

Paucity of initial cerebrospinal fluid inflammation in cryptococcal meningitis is associated with subsequent immune reconstitution inflammatory syndrome

DR Boulware, SC Bonham, DB Meya… - The Journal of …, 2010 - academic.oup.com
Abstract Background. Cryptococcal meningitis (CM)-related immune reconstitution
inflammatory syndrome (IRIS) complicates antiretroviral therapy (ART) in 20%–40% of ART …

Cryptococcus interactions with macrophages: evasion and manipulation of the phagosome by a fungal pathogen

SA Johnston, RC May - Cellular microbiology, 2013 - Wiley Online Library
C ryptococcus is a potentially fatal fungal pathogen and a leading cause of death in
immunocompromised patients. As an opportunistic and facultative intracellular pathogen of …

Host Immunity to Cryptococcus Neoformans

S Rohatgi, L Pirofski - Future microbiology, 2015 - Taylor & Francis
Cryptococcosis is caused by the fungal genus Cryptococcus. Cryptococcosis, predominantly
meningoencephalitis, emerged with the HIV pandemic, primarily afflicting HIV-infected …

The Intracellular Life of Cryptococcus neoformans

C Coelho, AL Bocca… - Annual Review of …, 2014 - annualreviews.org
Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …

Cryptococcus

SS Li, CH Mody - Proceedings of the American Thoracic Society, 2010 - atsjournals.org
Cryptococcus is a unique environmental fungus. Among the more than three dozen species
of Cryptococcus, only C. neoformans and C. gattii commonly cause disease. Although many …

Robust stimulation of humoral and cellular immune responses following vaccination with antigen-loaded β-glucan particles

H Huang, GR Ostroff, CK Lee, CA Specht, SM Levitz - MBio, 2010 - Am Soc Microbiol
ABSTRACT β-Glucan particles (GPs) are purified Saccharomyces cerevisiae cell walls
treated so that they are primarily β1, 3-d-glucans and free of mannans and proteins. GPs are …