Modelling approaches to particle deposition and clearance in the human respiratory tract

M Lazaridis - Air Quality, Atmosphere & Health, 2023 - Springer
Dosimetry models for the estimation of particle deposition in the human respiratory tract (RT)
in conjunction with clearance transport models are vital components to relate human …

Human Multi-Compartment Airways-on-Chip Platform for Emulating Respiratory Airborne Transmission: From Nose to Pulmonary Acini

E Nof, H Zidan, A Artzy-Schnirman… - Frontiers in …, 2022 - frontiersin.org
The past decade has witnessed tremendous endeavors to deliver novel preclinical in vitro
lung models for pulmonary research endpoints, including foremost with the advent of organ …

The fate of airborne microfibers in the human respiratory tract in different microenvironments

M Triantafyllaki, E Chalvatzaki, A Torres-Agullo… - Science of The Total …, 2024 - Elsevier
Αirborne microplastics (MPs) are considered an important exposure hazard to humans,
especially in the indoor environment. Deposition and clearance of MPs in the human …

Validating CFD predictions of nasal spray deposition: Inclusion of cloud motion effects for two spray pump designs

AV Kolanjiyil, S Hosseini, A Alfaifi… - Aerosol Science and …, 2022 - Taylor & Francis
Momentum transfer from nasal spray droplets to the surrounding gas may create droplet
cloud motion and influence nasal deposition patterns. The objective of this study was to …

3D computational fluid and particle dynamics simulations: metrics of aerosol capture by impaction filters

V Malavé, K Jeerage, E Garboczi… - Journal of Breath …, 2023 - iopscience.iop.org
Human studies provide valuable information on components or analytes recovered from
exhaled breath, but there are limitations due to inter-individual and intra-individual variation …

Validation and Sensitivity analysis for a nasal spray deposition computational model

H Calmet, D Oks, A Santiago, G Houzeaux… - International journal of …, 2022 - Elsevier
Validating numerical models against experimental models of nasal spray deposition is
challenging since many aspects must be considered. That being said, it is a critical step in …

A model study on the effect of human's height variability in particle deposition and retained dose in the respiratory tract

E Chalvatzaki, M Lazaridis - Environmental Science and Pollution …, 2024 - Springer
The objective of the current study was to investigate the impact of human's height variability
to the deposition percentage, the deposited and the retained dose of particulate matter in the …

[PDF][PDF] Understanding local respiratory toxicity and bioavailability of inhaled pesticides in an occupational exposure setting

Z Enlo-Scott - 2022 - kclpure.kcl.ac.uk
Background: Occupational exposure to xenobiotic aerosols may occur within different
settings, with a common example being the unintentional inhalation of pesticide aerosols …

Inhalation Biopharmaceutics

P Akhuemokhan, M Swedrowska… - … : From Fundamentals to …, 2022 - Wiley Online Library
Factors affecting deposition may be patient‐specific such as inspiratory profile, lung luminal
conditions, and airway geometry or drug product dependent such as inhalation device or …