A comparative analysis of microglial inducible Cre lines
TE Faust, PA Feinberg, C O'Connor, R Kawaguchi… - Cell reports, 2023 - cell.com
Cre/loxP technology has revolutionized genetic studies and allowed for spatial and temporal
control of gene expression in specific cell types. Microglial biology has particularly benefited …
control of gene expression in specific cell types. Microglial biology has particularly benefited …
Obesity-associated microglial inflammatory activation paradoxically improves glucose tolerance
Hypothalamic gliosis associated with high-fat diet (HFD) feeding increases susceptibility to
hyperphagia and weight gain. However, the body-weight-independent contribution of …
hyperphagia and weight gain. However, the body-weight-independent contribution of …
Microglia facilitate and stabilize the response to general anesthesia via modulating the neuronal network in a brain region-specific manner
General anesthesia leads to a loss of consciousness and an unrousable state in patients.
Although general anesthetics are widely used in clinical practice, their underlying …
Although general anesthetics are widely used in clinical practice, their underlying …
Microglial Nogo delays recovery following traumatic brain injury in mice
Abstract Nogo‐A, B, and C are well described members of the reticulon family of proteins,
most well known for their negative regulatory effects on central nervous system (CNS) …
most well known for their negative regulatory effects on central nervous system (CNS) …
Transgenic Targeting of Fcrls Creates a Highly Efficient Constitutively Active Microglia Cre Line with Differentiated Specificity
Microglia carry out important functions as the resident macrophages of the brain. To study
their role in health and disease, the research community needs tools to genetically modify …
their role in health and disease, the research community needs tools to genetically modify …
[HTML][HTML] An inducible genetic tool for tracking and manipulating specific microglial states in development and disease
KM Barclay, N Abduljawad, Z Cheng, MW Kim, L Zhou… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Recent single-cell RNA sequencing studies have revealed distinct microglial states in
development and disease. These include proliferative region-associated microglia (PAM) in …
development and disease. These include proliferative region-associated microglia (PAM) in …
TGF-β1 Regulation in the Context of Microglial Homeostasis Investigating the Source and Mechanisms of TGF-β Ligand Production and Signaling Regulation in the …
A Bedolla - 2023 - search.proquest.com
Microglia are essential components for normal brain functioning at homeostasis and during
disease or injury state. Recently it has become clear that TGF-β signaling is essential for …
disease or injury state. Recently it has become clear that TGF-β signaling is essential for …
[PDF][PDF] eScholarship@ UMassChan
TE Faust, PA Feinberg, C O'Connor, A Margaret… - repository.escholarship.umassmed …
Cre/loxP technology has revolutionized genetic studies and allowed for spatial and temporal
control of gene expression in specific cell types. Microglial biology has particularly benefited …
control of gene expression in specific cell types. Microglial biology has particularly benefited …