Nanotechnology-based drug delivery for the treatment of CNS disorders

KR Mittal, N Pharasi, B Sarna, M Singh… - Translational …, 2022 - degruyter.com
Approximately 6.8 million people die annually because of problems related to the central
nervous system (CNS), and out of them, approximately 1 million people are affected by …

Schizophrenia as metabolic disease. What are the causes?

AMN Helaly, DSED Ghorab - Metabolic Brain Disease, 2023 - Springer
Schizophrenia (SZ) is a devastating neurodevelopmental disease with an accelerated
ageing feature. The criteria of metabolic disease firmly fit with those of schizophrenia …

[HTML][HTML] Design, synthesis and cytotoxic evaluation of a selective serotonin reuptake inhibitor (SSRI) by virtual screening

DN Jaramillo, D Millán, J Guevara-Pulido - European Journal of …, 2023 - Elsevier
Depression is one of the most common mental illnesses, affecting almost 300 million people.
According to the WHO, depression is one of the world's leading causes of disability and …

[PDF][PDF] Фармакологические мишени и механизм действия антипсихотических средств в рамках нейрохимической теории патогенеза шизофрении

КЮ Калитин, АА Спасов, ОЮ Муха… - … журнал им. ИМ …, 2021 - rusjphysiol.org
Аннотация Шизофрения характеризуется нейрохимическими, морфологическими,
биоэлектрическими и поведенческими изменениями в организме, системная …

Improvement of synaptic plasticity by nanoparticles and the related mechanisms: Applications and prospects

A Chen, Y Kang, J Liu, J Wu, X Feng, M Wang… - Journal of Controlled …, 2022 - Elsevier
Synaptic plasticity is an important basis of learning and memory and participates in brain
network remodelling after different types of brain injury (such as that caused by …

Monophasic coamorphous sulpiride: a leap in physicochemical attributes and dual inhibition of GlyT1 and P-glycoprotein, supported by experimental and …

E Pardhi, DS Tomar, R Khemchandani… - Journal of …, 2024 - Taylor & Francis
Study aimed to design and development of a supramolecular formulation of sulpiride (SUL)
to enhance its solubility, dissolution and permeability by targeting a novel GlyT1 inhibition …

[HTML][HTML] Material Informatics-Driven Insights into Brain Cancer Nanocarriers: A Bibliometric Comparison of PLGA vs. Liposomes

BA Makalew, SA Abrori - OpenNano, 2024 - Elsevier
This study explores a comparative analysis of PLGA nanoparticles and liposomes as
potential carriers for brain cancer drug delivery, with a special focus on how material …

Antipsychotic prescription patterns and associated factors among the elderly with psychiatric illnesses

SW Cheng, CW Lu, HY Chan, JJ Chen… - International Clinical …, 2022 - journals.lww.com
Prescribing rate of antipsychotics in elderly patients with psychiatric illnesses has been
increasing all over the world. However, there is a lack of research examining the use of …

Neural Network-based Optimization of Silybum Marianum Extract-loaded Chitosan Particles: Modeling, Preparation and Antioxidant Evaluation

A Hanafi, KD Safa, S Rezazadeh - Current Computer-Aided …, 2023 - ingentaconnect.com
Background: Silymarin is a flavonolignan extracted from Silybum marianum with various
therapeutic applications. Many studies have focused on improving the bioavailability of …

Drug delivery nanosystems for neural regenerative medicine

S Kecel-Gunduz, B Bicak, AE Ozel - Neural Regenerative Nanomedicine, 2020 - Elsevier
Disorders in the brain and peripheral nervous system cause neurodegenerative diseases.
Many of the drugs commonly used in the diagnosis and treatment of neurodegenerative …