Enhancing cancer immunotherapy with nanomedicine
Therapeutic targeting of the immune system in cancer is now a clinical reality and marked
successes have been achieved, most notably through the use of checkpoint blockade …
successes have been achieved, most notably through the use of checkpoint blockade …
Improving cancer immunotherapy through nanotechnology
MS Goldberg - Nature Reviews Cancer, 2019 - nature.com
Abstract The 2018 Nobel Prize in Physiology or Medicine was awarded to pioneers in the
field of cancer immunotherapy, as the utility of leveraging a patient's coordinated and …
field of cancer immunotherapy, as the utility of leveraging a patient's coordinated and …
Near-infrared-triggered photodynamic therapy with multitasking upconversion nanoparticles in combination with checkpoint blockade for immunotherapy of colorectal …
While immunotherapy has become a highly promising paradigm for cancer treatment in
recent years, it has long been recognized that photodynamic therapy (PDT) has the ability to …
recent years, it has long been recognized that photodynamic therapy (PDT) has the ability to …
Surface modification strategies in translocating nano-vesicles across different barriers and the role of bio-vesicles in improving anticancer therapy
Nanovesicles and bio-vesicles (BVs) have emerged as promising tools to achieve targeted
cancer therapy due to their ability to overcome many of the key challenges currently being …
cancer therapy due to their ability to overcome many of the key challenges currently being …
Synthetic nanoparticles for vaccines and immunotherapy
The immune system plays a critical role in our health. No other component of human
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …
Scaffolds that mimic antigen-presenting cells enable ex vivo expansion of primary T cells
Therapeutic ex vivo T-cell expansion is limited by low rates and T-cell products of limited
functionality. Here we describe a system that mimics natural antigen-presenting cells (APCs) …
functionality. Here we describe a system that mimics natural antigen-presenting cells (APCs) …
[HTML][HTML] Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy
Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …
against cancers. Despite these advancements, challenges remain, particularly in the clinical …
Extended release of perioperative immunotherapy prevents tumor recurrence and eliminates metastases
CG Park, CA Hartl, D Schmid, EM Carmona… - Science translational …, 2018 - science.org
Cancer immunotherapy can confer durable benefit, but the percentage of patients who
respond to this approach remains modest. The ability to concentrate immunostimulatory …
respond to this approach remains modest. The ability to concentrate immunostimulatory …
Nanoparticle-based immunotherapy for cancer
The design of nanovaccines capable of triggering effective antitumor immunity requires an
understanding of how the immune system senses and responds to threats, including …
understanding of how the immune system senses and responds to threats, including …
[HTML][HTML] Delivering safer immunotherapies for cancer
Cancer immunotherapy is now a powerful clinical reality, with a steady progression of new
drug approvals and a massive pipeline of additional treatments in clinical and preclinical …
drug approvals and a massive pipeline of additional treatments in clinical and preclinical …