Advances in oral drug delivery for regional targeting in the gastrointestinal tract-influence of physiological, pathophysiological and pharmaceutical factors
S Hua - Frontiers in pharmacology, 2020 - frontiersin.org
The oral route is by far the most common route of drug administration in the gastrointestinal
tract and can be used for both systemic drug delivery and for treating local gastrointestinal …
tract and can be used for both systemic drug delivery and for treating local gastrointestinal …
Clinical translation of advanced colonic drug delivery technologies
Targeted drug delivery to the colon offers a myriad of benefits, including treatment of local
diseases, direct access to unique therapeutic targets and the potential for increasing …
diseases, direct access to unique therapeutic targets and the potential for increasing …
A review of advanced oral drug delivery technologies facilitating the protection and absorption of protein and peptide molecules
BF Choonara, YE Choonara, P Kumar… - Biotechnology …, 2014 - Elsevier
The oral delivery of proteins and peptides is a dynamic research field despite the numerous
challenges limiting their effective delivery. Successful oral delivery of proteins and peptides …
challenges limiting their effective delivery. Successful oral delivery of proteins and peptides …
Nano-and microparticulate drug carriers for targeting of the inflamed intestinal mucosa
Conventional treatment of inflammatory bowel disease (IBD) is based on the daily
administration of high doses of immune-suppressant or anti-inflammatory drugs, often …
administration of high doses of immune-suppressant or anti-inflammatory drugs, often …
Pectin matrix as oral drug delivery vehicle for colon cancer treatment
Colon cancer is the fourth most common cancer globally with 639,000 deaths reported
annually. Typical chemotherapy is provided by injection route to reduce tumor growth and …
annually. Typical chemotherapy is provided by injection route to reduce tumor growth and …
[图书][B] Pharmaceutical Dosage Forms and Drug Delivery: Revised and Expanded
RI Mahato, AS Narang - 2017 - taylorfrancis.com
Completely revised and updated, this third edition of Pharmaceutical Dosage Forms and
Drug Delivery elucidates the basic principles of pharmaceutics, biopharmaceutics, dosage …
Drug Delivery elucidates the basic principles of pharmaceutics, biopharmaceutics, dosage …
Injection molding and its application to drug delivery
L Zema, G Loreti, A Melocchi, A Maroni… - Journal of controlled …, 2012 - Elsevier
Injection Molding (IM) consists in the injection, under high pressure conditions, of heat-
induced softened materials into a mold cavity where they are shaped. The advantages the …
induced softened materials into a mold cavity where they are shaped. The advantages the …
Microspheres for targeted drug delivery-A review on recent applications
Microspheres are one of the most explored drug carriers for site-specific delivery of cargoes
in a controlled and sustained manner. They are biocompatible, biodegradable, and are …
in a controlled and sustained manner. They are biocompatible, biodegradable, and are …
The Chronotopic™ system for pulsatile and colonic delivery of active molecules in the era of precision medicine: Feasibility by 3D printing via fused deposition …
A Melocchi, M Uboldi, F Briatico-Vangosa… - Pharmaceutics, 2021 - mdpi.com
The pulsatile-release Chronotopic™ system was conceived of as a drug-containing core
surrounded by a coat made of swellable/soluble hydrophilic polymers, the latter being able …
surrounded by a coat made of swellable/soluble hydrophilic polymers, the latter being able …
Oral colon-specific therapeutic approaches toward treatment of inflammatory bowel disease
Introduction: Inflammatory bowel disease (IBD) is a chronic relapsing idiopathic disease. In
clinical terms, most patients require lifelong medication associated with possible unpleasant …
clinical terms, most patients require lifelong medication associated with possible unpleasant …