Hepatitis a

RS Koff - The Lancet, 1998 - thelancet.com
Epidemiology The incubation period of hepatitis A is 15–50 days, with a mean of about 30
days. HAV is excreted in the faeces for 1–2 weeks before the onset of illness, and for at least …

Epaxal®: a virosomal vaccine to prevent hepatitis A infection

PA Bovier - Expert review of vaccines, 2008 - Taylor & Francis
Over the last few decades, different types of inactivated hepatitis A virus (HAV) vaccines
have been developed: several aluminum-adjuvanted vaccines and an aluminum-free …

Vaccines to prevent viral hepatitis

SM Lemon, DL Thomas - New England journal of medicine, 1997 - Mass Medical Soc
At least five different viruses cause hepatitis in humans. Two—hepatitis A virus (HAV) and
hepatitis E virus (HEV)—are nonenveloped RNA viruses that are spread predominantly by …

The virosome concept for influenza vaccines

A Huckriede, L Bungener, T Stegmann, T Daemen… - Vaccine, 2005 - Elsevier
There is a need for more efficacious inactivated influenza vaccines, since current
formulations show suboptimal immunogenicity in at-risk populations, like the elderly. More …

Hepatitis A booster vaccination: is there a need?

P Van Damme, J Banatvala, O Fay, S Iwarson… - The lancet, 2003 - thelancet.com
Hepatitis A is one of the most common vaccine-preventable infectious diseases in the world.
Effective vaccines against hepatitis A have been available since 1992, and they provide …

Liposomal adjuvants for human vaccines

CR Alving, Z Beck, GR Matyas… - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Liposomes are well-known as drug carriers, and are now critical components of
two of six types of adjuvants present in licensed vaccines. The liposomal vaccine adjuvant …

Liposomes and ISCOMS as vaccine formulations

GFA Kersten, DJA Crommelin - … et Biophysica Acta (BBA)-Reviews on …, 1995 - Elsevier
Numerous vehicles exist to present antigens to the immune system (Table 1). This review
focuses on two types of promising lipid particulate systems: liposomes and ISCOMs. The …

Immunogenicity and protectivity of a new liposomal hepatitis A vaccine

F Ambrosch, G Wiedermann, S Jonas, B Althaus… - Vaccine, 1997 - Elsevier
In this study we investigated a new liposomal hepatitis A vaccine (Epaxal®) developed by
the Swiss Serum and Vaccine Institute clinically and immunologically using a one dose …

Hepatitis A

N Previsani, D Lavanchy, G Siegl - Perspectives in Medical Virology, 2003 - Elsevier
Publisher Summary This chapter provides an overview of Hepatitis A, one of the oldest
diseases known to humankind. Hepatitis A is a self-limited disease that results in fulminant …

A SARS-CoV-2 Wuhan spike virosome vaccine induces superior neutralization breadth compared to one using the Beta spike

YU van der Velden, M Grobben, TG Caniels… - Scientific reports, 2022 - nature.com
Current SARS-CoV-2 vaccines are effective, but long-term protection is threatened by the
emergence of virus variants. We generated a virosome vaccine containing the Beta spike …