Flavonoids nanoparticles in cancer: Treatment, prevention and clinical prospects

H Khan, H Ullah, M Martorell, SE Valdes… - Seminars in cancer …, 2021 - Elsevier
The conventional therapies for cancer have a major concern of poor accessibility to tumor
tissues. Furthermore, the requirement of higher doses and non-selective nature of …

The coming age of flavonoids in the treatment of diabetic complications

T Caro-Ordieres, G Marín-Royo, L Opazo-Ríos… - Journal of clinical …, 2020 - mdpi.com
Diabetes mellitus (DM), and its micro and macrovascular complications, is one of the biggest
challenges for world public health. Despite overall improvement in prevention, diagnosis …

[HTML][HTML] Advancements in clinical translation of flavonoid nanoparticles for cancer treatment

T Sharma, D Singh, A Mahapatra, P Mohapatra… - OpenNano, 2022 - Elsevier
Cancer therapy has achieved new heights with numerous advancements made in this field
still, cancer treatment modalities including chemotherapy, radiotherapy, immunotherapy …

Recent advances in the biosynthesis, structure–activity relationships, formulations, pharmacology, and clinical trials of fisetin

R Zhong, MA Farag, M Chen, C He, J Xiao - EFood, 2022 - Wiley Online Library
Fisetin is one of the most popular flavonoids found in vegetables and fruits with several
health benefits such as antidiabetic, anticancer, and anti‐inflammatory activities …

Implications of flavonoids as potential modulators of cancer neovascularity

A Liskova, L Koklesova, M Samec, E Varghese… - Journal of cancer …, 2020 - Springer
Purpose The formation of new blood vessels from previous ones, angiogenesis, is critical in
tissue repair, expansion or remodeling in physiological processes and in various …

Drug delivery systems and flavonoids: Current knowledge in melanoma treatment and future perspectives

C Cunha, AL Daniel-da-Silva, H Oliveira - Micromachines, 2022 - mdpi.com
Melanoma is an aggressive form of skin cancer with a high prevalence in the population. An
early diagnosis is crucial to cure this disease. Still, when this is not possible, combining …

Mesoporous silica-based nanocarriers with dual response to pH and ROS for enhanced anti-inflammation therapy of 5-demethylnobiletin against psoriasis-like lesions

Y Wang, Y Zhang, Z Yang, L Zhang, X Chen… - International Journal of …, 2023 - Elsevier
Psoriasis is an inflammatory skin disease accompanied with chronic papulosquamous
lesions and multiple comorbidities that considerably affect patients' quality of life. In order to …

Flavonoids from Seabuckthorn (Hippophae rhamnoides L.) mimic neurotrophic functions in inducing neurite outgrowth in cultured neurons: signaling via PI3K/Akt and …

CX Xia, AX Gao, TTX Dong, KWK Tsim - Phytomedicine, 2023 - Elsevier
Background Various brain disorders, including neurodegenerative diseases and major
depressive disorders, threaten an increasing number of patients. Seabuckthorn, a fruit from …

Mitochondrial-induced epigenetic modifications: from biology to clinical translation

J Sharma, R Kumari, A Bhargava… - Current …, 2021 - ingentaconnect.com
Mitochondria are maternally inherited semi-autonomous organelles that play a central role
in redox balance, energy metabolism, control of integrated stress responses, and cellular …

Recent strategies for cancer therapy: polymer nanoparticles carrying medicinally important phytochemicals and their cellular targets

M Yıldırım, M Sessevmez, S Poyraz, N Düzgüneş - Pharmaceutics, 2023 - mdpi.com
Cancer is a leading cause of death in the world today. In addition to the side effects of the
chemotherapeutic drugs used to treat cancer, the development of resistance to the drugs …