Urinary tract infections (UTIs) are one of the most common pathological conditions in both
community and hospital settings. It has been estimated that about 150 million people …

Most bacterial pathogens have the remarkable ability to flourish in the external environment
and in specialized host niches. This ability requires their metabolism, physiology, and …

In many γ‐proteobacteria, the conserved GacS/GacA (BarA/UvrY) two‐component system
positively controls the expression of one to five genes specifying small RNAs (sRNAs) that …

Biofilms are communities of surface‐attached, matrix‐embedded microbial cells that can
resist antimicrobial chemotherapy and contribute to persistent infections. Using an …

Escherichia coli ordinarily resides in the lower gastrointestinal tract in humans, but some
strains, known as Uropathogenic E. coli (UPEC), are also adapted to the relatively harsh …

The two-component signal transduction system (TCS) BarA/UvrY activates transcription of
CsrB and CsrC noncoding RNAs, which act by sequestering the RNA-binding global …

Bacteria lose or gain genetic material and through selection, new variants become fixed in
the population. Here we provide the first, genome-wide example of a single bacterial strain's …

The importance of Csr post-transcriptional systems is gradually emerging; these systems
control a variety of virulence-linked physiological traits in many pathogenic bacteria. This …

Extra-intestinal pathogenic E. coli (ExPEC) infections are common in mammals and birds.
The predominant ExPEC types are avian pathogenic E. coli (APEC), neonatal meningitis …

The general stress sigma factor RpoS (σ s) is induced buring entry into stationary phase and
in response to multiple stress conditions. RpoS is regulated at the levels of transcription …