Inborn errors of immunity (IEI) are a heterogenous group of disorders driven by genetic
defects that functionally impact the development and/or function of the innate and/or …

Systemic autoinflammatory disorders comprise an expanding group of rare conditions. They
are mediated by dysfunction of the innate immune system and share a core of phenotypic …

Objective Persistent inflammation is an insidious and less studied feature of FMF. We
investigated clinical determinants of persistent inflammation and its associations with …

Abstract Familial Mediterranean Fever (FMF) is an autosomal recessive autoinflammatory
disease caused by mutations in the MEFV (ME diterranean F e V er) gene that affects people …

Background The objective of this initiative was to develop a treat-to-target (T2T) approach for
the management of patients with Familial Mediterranean Fever (FMF), including the …

Objective. The diagnosis of familial Mediterranean fever (FMF) can be missed or delayed
even in countries where FMF prevalence is high. In this study we investigated the …

Иммуновоспалительные заболевания сегодня рассматривают как континуум,
предполагающий сложное взаимодействие нарушений врожденного (аутовоспаление) …

Familial Mediterranean fever (FMF) is the most prevalent monogenic autoinflammatory
disorder, characterized by recurrent fever and serositis. It primarily affects individuals of …

Objectives To define the demographic, clinical and genetic features of familial
Mediterranean fever (FMF) patients with early disease onset and to compare them with late …

Familial Mediterranean fever (FMF) is a hereditary, autoinflammatory disease characterized
by recurrent fever and serositis attacks. The disease onset occurs before 20 years of age in …