Astronaut omics and the impact of space on the human body at scale

LA Rutter, H Cope, MJ MacKay, R Herranz… - Nature …, 2024 - nature.com
Future multi-year crewed planetary missions will motivate advances in aerospace nutrition
and telehealth. On Earth, the Human Cell Atlas project aims to spatially map all cell types in …

[HTML][HTML] Routine omics collection is a golden opportunity for European human research in space and analog environments

H Cope, CRG Willis, MJ MacKay, LA Rutter, LS Toh… - Patterns, 2022 - cell.com
Widespread generation and analysis of omics data have revolutionized molecular medicine
on Earth, yet its power to yield new mechanistic insights and improve occupational health …

Skeletal muscle gene expression dysregulation in long-term spaceflights and aging is clock-dependent

D Malhan, M Yalçin, B Schoenrock, D Blottner… - npj …, 2023 - nature.com
The circadian clock regulates cellular and molecular processes in mammals across all
tissues including skeletal muscle, one of the largest organs in the human body …

Caenorhabditis elegans in microgravity: An omics perspective

A Scott, CRG Willis, M Muratani, A Higashitani… - Iscience, 2023 - cell.com
The application of omics to study Caenorhabditis elegans (C. elegans) in the context of
spaceflight is increasing, illuminating the wide-ranging biological impacts of spaceflight on …

How to obtain an integrated picture of the molecular networks involved in adaptation to microgravity in different biological systems?

CRG Willis, M Calvaruso, D Angeloni, S Baatout… - npj …, 2024 - nature.com
Abstract Periodically, the European Space Agency (ESA) updates scientific roadmaps in
consultation with the scientific community. The ESA SciSpacE Science Community White …

Multiscale modeling in the framework of biological systems and its potential for spaceflight biology studies

A Millar-Wilson, Ó Ward, E Duffy, G Hardiman - Iscience, 2022 - cell.com
A central tenet of systems biology is that biological systems are greater than the sum of their
component parts. Spaceflight is associated with hazards including radiation exposure and …

Research progress on the effects of microgravity and space radiation on astronauts' health and nursing measures

X Cao - Open Astronomy, 2022 - degruyter.com
With the development of human space technology, more and more astronauts fly into space.
With the rapid development of commercial aerospace, more ordinary people will go to space …

MCAST'S Aerospace Program in Malta: An Overview of Technological Advancements and International Collaborations

L Barilaro, L Olivieri, M Wylie, G Rodeghiero… - Aerotecnica Missili & …, 2024 - Springer
Abstract The Aerospace Program at the Malta College of Arts, Science and Technology
(MCAST) is a research and development program that focuses on addressing challenges in …

Enhancing European capabilities for application of multi-omics studies in biology and biomedicine space research

A Manzano, S Weging, D Bezdan, J Borg, T Cahill… - Iscience, 2023 - cell.com
Following on from the NASA twins' study, there has been a tremendous interest in the use of
omics techniques in spaceflight. Individual space agencies, NASA's GeneLab, JAXA's …