In the past few decades, the placenta became a very controversial topic that has had many
researchers and pharmacists discussing the significance of the effects of pharmaceutical …

Background Maternal-to-fetal transfer of antiretroviral drugs contributes to prevention of
vertical transmission of HIV. Objective This systematic review discusses published studies …

Objective: Studying the biology of the human placenta represents a major experimental
challenge. Although conventional cell culture techniques have been used to study different …

A key goal of managing HIV in pregnancy and postpartum is to optimise a woman's own
health. Furthermore, one of the major successes in the management of individuals living …

One of the major successes in the management of HIV-positive patients has been the
PMTCT of HIV-1. With the widespread implementation of routine antenatal screening for HIV …

One of the major successes in the management of HIV-positive patients has been the
prevention of mother-tochild transmission (MTCT) of HIV-1. With the widespread …

The aim of our study was to evaluate the bidirectional transfer of Bisphenol S (BPS) and its
main metabolite, BPS Glucuronide (BPSG), using the model of perfused human placenta …

Data on placental transfer is lacking for the recent HIV integrase inhibitors, bictegravir and
cabotegravir, although their future use in pregnancy is to be expected. The objective of this …

HIV resides within anatomical 'sanctuary sites' where local drug exposure and viral
dynamics may differ significantly from the systemic compartment. Widespread …

Objective To determine the transplacental pharmacokinetics of the HIV integrase inhibitor
dolutegravir. Study design Maternal-to-fetal transfer across the term human placenta was …