Adiponectin (a protein consisting of 244 amino acids and characterized by a molecular
weight of 28 kDa) is a cytokine that is secreted from adipose tissues (adipokine). Available …

Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

Obesity has been associated with increased incidence and mortality of a wide variety of
human cancers including colorectal cancer. However, the molecular mechanism by which …

Under normal physiological conditions, leptin and the leptin receptor (ObR) regulate the
body weight by balancing food intake and energy expenditure. However, this adipocyte …

Background and objectives Obesity is associated with metabolic dysfunction and over
nutrition. Increased body mass index and obesity are strongly amalgamated with changes in …

O-linked N-acetylglucosaminylation (O-GlcNAcylation) is a reversible post-translational
modification consisting in the addition of a sugar moiety to serine/threonine residues of …

Metabolic syndrome (MS) is characterized by a group of metabolic disturbances which lead
to an enhanced risk of cardiovascular diseases and type 2 diabetes mellitus. MS constitutes …

Several studies report varying incidence rates of cancer in subsites of the colorectum, as an
increasing proportion appears to develop in the proximal colon. Varying incidence trends …

The peroxisome proliferator-activated receptors, PPARα, PPARβ, and PPARγ, are a family of
transcription factors activated by a diversity of molecules including fatty acids and fatty acid …

Obesity is a complex disease caused by the interaction of a myriad of genetic, dietary,
lifestyle and environmental factors, which favors a chronic positive energy balance, leading …