TERT—regulation and roles in cancer formation

M Dratwa, B Wysoczańska, P Łacina, T Kubik… - Frontiers in …, 2020 - frontiersin.org
Telomerase reverse transcriptase (TERT) is a catalytic subunit of telomerase. Telomerase
complex plays a key role in cancer formation by telomere dependent or independent …

The emerging role of the androgen receptor in bladder cancer

AP Lombard, M Mudryj - Endocrine-related cancer, 2015 - erc.bioscientifica.com
Men are three to four times more likely to get bladder cancer than women. The gender
disparity characterizing bladder cancer diagnoses has been investigated. One hypothesis is …

Cumulative evidence for relationships between multiple variants in the TERT and CLPTM1L region and risk of cancer and non-cancer disease

J Tian, Y Wang, Y Dong, J Chang, Y Wu… - Frontiers in …, 2022 - frontiersin.org
Background Genetic studies previously reported that variants in TERT-CLPTM1L genes
were related to susceptibility of cancer and non-cancer diseases. However, conclusions …

Physiological functions of urea transporter B

L Yu, T Liu, S Fu, L Li, X Meng, X Su, Z Xie… - … -European Journal of …, 2019 - Springer
Urea transporters (UTs) are membrane proteins in the urea transporter protein A (UT-A) and
urea transporter protein B (UT-B) families. UT-B is mainly expressed in endothelial cell …

TERT Gene rs2736100 and rs2736098 polymorphisms are associated with increased cancer risk: a meta-analysis

X Zhang, Y Chen, D Yan, J Han, L Zhu - Biochemical Genetics, 2022 - Springer
Abnormal telomerase activity plays a key role in the development of carcinogenesis. The
variants rs2736100 and rs2736098 of the telomerase reverse transcriptase (TERT) gene …

Genome-wide association studies and epigenome-wide association studies go together in cancer control

M Verma - Future Oncology, 2016 - Taylor & Francis
Completion of the human genome a decade ago laid the foundation for: using genetic
information in assessing risk to identify individuals and populations that are likely to develop …

SLC14A1: a novel target for human urothelial cancer

R Hou, X Kong, B Yang, Y Xie, G Chen - Clinical and Translational …, 2017 - Springer
Urinary bladder cancer is the second commonly diagnosed genitourinary malignancy.
Previously, bio-molecular alterations have been observed within certain locations such as …

The TERT locus genotypes of rs2736100-CC/CA and rs2736098-AA predict shorter survival in renal cell carcinoma

R Ma, C Liu, M Lu, X Yuan, G Cheng, F Kong… - … Oncology: Seminars and …, 2019 - Elsevier
Objectives The single nucleotide polymorphisms (SNPs) at the TERT rs2736100 and
rs2736098 are associated with multicancer susceptibility, however, published findings …

Urea transport and clinical potential of urearetics

JD Klein, JM Sands - Current opinion in nephrology and …, 2016 - journals.lww.com
Urea transport and clinical potential of urearetics : Current Opinion in Nephrology and
Hypertension Urea transport and clinical potential of urearetics : Current Opinion in Nephrology …

[PDF][PDF] New evidence of TERT rs2736098 polymorphism and cancer risk: an updated meta-analysis

T Li, Y Xian, T Tian, X Zhuang, M Chu - J BUON, 2016 - jbuon.com
Purpose: Previous meta-analyses didn't suggest any significant association between TERT
rs2736098 polymorphism and overall cancer risk, and the existing evidence lacks statistical …