Neutrophil extracellular trap (NET) formation, first described in 2004 as a previously
unknown strategy of neutrophils to fight microbes, has attracted an increasing interest in the …

Ischemic thrombotic disease, characterized by the formation of obstructive blood clots within
arteries or veins, is a condition associated with life-threatening events, such as stroke …

Over the past years, neutrophil extracellular traps (NETs) were shown to contribute to states
of acute and chronic inflammatory disease. They are composed of expelled chromatin and …

Neutrophil extracellular traps (NETs) have been implicated in the pathogenesis of
abdominal aortic aneurysms (AAAs). This study has addressed the notion that NET …

Background Neutrophils participate in the pathogenesis of thrombosis through the formation
of neutrophil extracellular traps (NETs). Thrombosis is the main cause of morbidity and …

The hypercoagulable state associated with malignancy is well described. However, the
mechanisms by which tumors cause this hypercoagulable state are yet to be fully …

Essential thrombocythemia (ET) is comprised among chronic myeloproliferative neoplasms
(MPN) and is caused by driver mutations in JAK 2, CALR, and MPL, which lead to …

Thrombosis, both in arterial and venous territories, is the major complication of
myeloproliferative neoplasms and is responsible for a high rate of morbidity and mortality …

Interferon-based therapies, such as ropeginterferon alfa-2b have emerged as promising
disease-modifying agents for myeloproliferative neoplasms (MPNs), including essential …

Platelets are anucleate blood cells that play key roles in thrombosis and hemostasis.
Platelets are also effector cells in malignancy and are known to home into the …