Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs
Abstract According to the Alzheimer Association Report (2017), Alzheimer's disease (AD) is
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …
Recent developments in industrial applications of nanoemulsions
Nanotechnology is being utilized in various industries to increase the quality, safety, shelf-
life, and functional performance of commercial products. Nanoemulsions are …
life, and functional performance of commercial products. Nanoemulsions are …
Nanoemulsions: formation, properties and applications
Nanoemulsions are kinetically stable liquid-in-liquid dispersions with droplet sizes on the
order of 100 nm. Their small size leads to useful properties such as high surface area per …
order of 100 nm. Their small size leads to useful properties such as high surface area per …
[HTML][HTML] Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics
Central nervous system (CNS) disorders (eg, multiple sclerosis, Alzheimer's disease, etc.)
represent a growing public health issue, primarily due to the increased life expectancy and …
represent a growing public health issue, primarily due to the increased life expectancy and …
Nanoemulsions for “nose-to-brain” drug delivery
The blood–brain barrier (BBB) plays a fundamental role in protecting the brain from toxic
substances and therefore also controls and restricts the entry of therapeutic agents. The …
substances and therefore also controls and restricts the entry of therapeutic agents. The …
Chitosan in nasal delivery systems for therapeutic drugs
L Casettari, L Illum - Journal of Controlled Release, 2014 - Elsevier
There is an obvious need for efficient and safe nasal absorption enhancers for the
development of therapeutically efficacious nasal products for small hydrophilic drugs …
development of therapeutically efficacious nasal products for small hydrophilic drugs …
Formation, characteristics and oil industry applications of nanoemulsions: A review
Nanoemulsions are kinetically stable homogeneous dispersions of immiscible liquids with
droplet sizes in the order of 500 nm. The nano-size droplets are advantageous in enhancing …
droplet sizes in the order of 500 nm. The nano-size droplets are advantageous in enhancing …
Evolving drug delivery strategies to overcome the blood brain barrier
DS Hersh, AS Wadajkar, NB Roberts… - Current …, 2016 - ingentaconnect.com
The blood-brain barrier (BBB) poses a unique challenge for drug delivery to the central
nervous system (CNS). The BBB consists of a continuous layer of specialized endothelial …
nervous system (CNS). The BBB consists of a continuous layer of specialized endothelial …
Direct nose to brain drug delivery via integrated nerve pathways bypassing the blood–brain barrier: an excellent platform for brain targeting
CV Pardeshi, VS Belgamwar - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: The blood–brain barrier (BBB) represents a stringent barrier for delivery of
neurotherapeutics in vivo. An attempt to overcome this barrier is represented by the direct …
neurotherapeutics in vivo. An attempt to overcome this barrier is represented by the direct …
Nanotechnological advances for the delivery of CNS therapeutics
Effective non-invasive treatment of neurological diseases is often limited by the poor access
of therapeutic agents into the central nervous system (CNS). The majority of drugs and …
of therapeutic agents into the central nervous system (CNS). The majority of drugs and …