Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course

X Zhou, R Baumann, X Gao, M Mendoza, S Singh… - Cell, 2022 - cell.com
Changes in gut microbiota have been associated with several diseases. Here, the
International Multiple Sclerosis Microbiome Study (iMSMS) studied the gut microbiome of …

Feeding the gut microbiome: impact on multiple sclerosis

M Bronzini, A Maglione, R Rosso, M Matta… - Frontiers in …, 2023 - frontiersin.org
Multiple sclerosis (MS) is a multifactorial neurological disease characterized by chronic
inflammation and immune-driven demyelination of the central nervous system (CNS). The …

Latent potential of multifunctional selenium nanoparticles in neurological diseases and altered gut microbiota

H Ashraf, D Cossu, S Ruberto, M Noli, S Jasemi… - Materials, 2023 - mdpi.com
Neurological diseases remain a major concern due to the high world mortality rate and the
absence of appropriate therapies to cross the blood–brain barrier (BBB). Therefore, the …

Bacterial variation in the oral microbiota in multiple sclerosis patients

Z Zangeneh, A Abdi-Ali, K Khamooshian, A Alvandi… - PLoS …, 2021 - journals.plos.org
Background Microorganisms in oral cavity are called oral microbiota, while microbiome
consists of total genome content of microorganisms in a host. Interaction between host and …

Molecular modification of Kex2 P1'site enhances expression and druggability of fungal defensin

Y Jin, N Yang, D Teng, Y Hao, R Mao, J Wang - Antibiotics, 2023 - mdpi.com
Pichia pastoris is the widely used expression system for producing recombinant secretory
proteins. It is known that Kex2 protease plays a vital role in the process of protein secretion …

Lactiplantibacillus (Lactobacillus) plantarum as a Complementary Treatment to Improve Symptomatology in Neurodegenerative Disease: A Systematic Review of …

AI Beltrán-Velasco, M Reiriz, S Uceda… - International Journal of …, 2024 - mdpi.com
This systematic review addresses the use of Lactiplantibacillus (Lactobacillus) plantarum in
the symptomatological intervention of neurodegenerative disease. The existence of gut …

Host genetics and gut microbiome: perspectives for multiple sclerosis

A Maglione, M Zuccalà, M Tosi, M Clerico, S Rolla - Genes, 2021 - mdpi.com
As a complex disease, Multiple Sclerosis (MS)'s etiology is determined by both genetic and
environmental factors. In the last decade, the gut microbiome has emerged as an important …

The association between various viral infections and multiple sclerosis: An umbrella review on systematic review and meta‐analysis

A Bakhshi, N Eslami, N Norouzi… - Reviews in Medical …, 2024 - Wiley Online Library
Multiple Sclerosis (MS) is one of the immune‐mediated demyelinating disorders. Multiple
components, including the environment and genetics, are possible factors in the …

Multi-omic analysis of the gut microbiome in rats with lithium-pilocarpine-induced temporal lobe epilepsy

MET Oliveira, GVB Paulino, ED dos Santos Júnior… - Molecular …, 2022 - Springer
Evidence supports that the gut microbiota and bacteria-dependent metabolites influence the
maintenance of epileptic brain activity. However, the alterations in the gut microbiota …

PD‐1/PD‐L1 blockade: Prospectives for immunotherapy in cancer and autoimmunity

R Hosseinzadeh, F Feizisani, N Shomali… - IUBMB …, 2021 - Wiley Online Library
Immune checkpoint blockade therapy (ICBT) has become a successful cancer treatment
approach in the field of cancer immunotherapy. Blockade of programmed death 1 (PD‐1) …