Celiac disease (CD) is one of the most common diseases, resulting from both environmental
(gluten) and genetic factors [human leukocyte antigen (HLA) and non-HLA genes]. The …

Celiac disease has become one of the best-understood HLA-linked disorders. Although it
shares many immunologic features with inflammatory bowel disease, celiac disease is …

The prevalence of Parkinson's disease (PD) increases with age and is projected to increase
in parallel to the rising average age of the population. The disease can have significant …

Tissue transglutaminase (TG2) catalyzes the cross-linking of proteins by the formation of
isopeptide bonds between glutamine (Gln) and lysine (Lys) side chains. Although TG2 is …

Mesoionic carbenes have found wide use as components of homogeneous catalysts.
Recent discoveries have, however, shown that metal complexes of such ligands also have …

InhA, the enoyl reductase from the mycobacterial type II fatty acid biosynthesis pathway, is a
target for the development of novel drugs against tuberculosis. We exploited copper …

Tissue transglutaminase (TG2) is a calcium-dependent enzyme that catalyses several acyl
transfer reactions. The most biologically relevant of these involve protein-bound Gln …

Background Wheat is one of the main foods of the human diet. It contains a protein complex,
gluten, which is primarily responsible for the rheological behavior of wheat flours. However …

Transglutaminase type 2 (TG2) is a ubiquitously expressed member of the transglutaminase
family, capable of mediating a transamidation reaction between a variety of protein …

A microwave-assisted, one-pot, three-step Sonogashira cross-coupling− desilylation−
cycloaddition sequence was developed for the convenient preparation of 1, 4-disubstituted …