A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities

MA Ortega, O Fraile-Martinez, C García-Montero… - Military Medical …, 2023 - Springer
Spinal cord injury (SCI) is a devastating and disabling medical condition generally caused
by a traumatic event (primary injury). This initial trauma is accompanied by a set of biological …

Single-cell analysis reveals region-heterogeneous responses in rhesus monkey spinal cord with complete injury

Y Fan, X Wu, S Han, Q Zhang, Z Sun, B Chen… - Nature …, 2023 - nature.com
Spinal cord injury (SCI) leads to severe sensory and motor dysfunction below the lesion.
However, the cellular dynamic responses and heterogeneity across different regions below …

Development and application of three-dimensional bioprinting scaffold in the repair of spinal cord injury

D Lu, Y Yang, P Zhang, Z Ma, W Li, Y Song… - Tissue Engineering and …, 2022 - Springer
Spinal cord injury (SCI) is a disabling and destructive central nervous system injury that has
not yet been successfully treated at this stage. Three-dimensional (3D) bioprinting has …

Extent of cord pathology in the lumbosacral enlargement in non-traumatic versus traumatic spinal cord injury

G David, K Vallotton, M Hupp, A Curt… - Journal of …, 2022 - liebertpub.com
This study compares remote neurodegenerative changes caudal to a cervical injury in
degenerative cervical myelopathy (DCM; ie, non-traumatic) and incomplete traumatic spinal …

[HTML][HTML] Clinical assessment and management of acute spinal cord injury

C Quinones, JP Wilson Jr, D Kumbhare… - Journal of Clinical …, 2024 - mdpi.com
The information contained in this article is suitable for clinicians practicing in the United
States desiring a general overview of the assessment and management of spinal cord injury …

Spinal cord atrophy after spinal cord injury–A systematic review and meta-analysis

C Trolle, E Goldberg, C Linnman - NeuroImage: Clinical, 2023 - Elsevier
Cervical spinal cord atrophy occurs after spinal cord injury. The atrophy and how level of
injury affects atrophy differs between studies. A systematic review and metaanalysis were …

Longitudinal motor system changes from acute to chronic spinal cord injury

TM Emmenegger, D Pfyffer, A Curt… - European Journal of …, 2024 - Wiley Online Library
Background and purpose In acute spinal cord injury (SCI), magnetic resonance imaging
(MRI) reveals tissue bridges and neurodegeneration for 2 years. This 5‐year study aims to …

In Vivo and 3D Imaging Technique(s) for Spatiotemporal Mapping of Pathological Events in Experimental Model(s) of Spinal Cord Injury

D Goyal, H Kumar - ACS chemical neuroscience, 2023 - ACS Publications
Endothelial damage, astrogliosis, microgliosis, and neuronal degeneration are the most
common events after spinal cord injury (SCI). Studies highlighted that studying the …

ACID: A Comprehensive Toolbox for Image Processing and Modeling of Brain, Spinal Cord, and Ex Vivo Diffusion MRI Data

G David, B Fricke, JM Oeschger, L Ruthotto, FJ Fritz… - bioRxiv, 2023 - biorxiv.org
Diffusion MRI (dMRI) has become a crucial imaging technique in the field of neuroscience,
with a growing number of clinical applications. Although most studies still focus on the brain …

Spinal cord pathology revealed by MRI in traumatic spinal cord injury

D Pfyffer, P Freund - Current Opinion in Neurology, 2021 - journals.lww.com
Neuroimaging biomarkers reveal focal and remote cord pathology. These biomarkers show
sensitivity to the underlying disease processes and are clinically eloquent. Thus, they …