The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

The IL-1 cytokine family comprises 11 members (7 ligands with agonist activity, 3 receptor
antagonists and 1 anti-inflammatory cytokine) and is recognised as a key mediator of …

Interleukin 33 (IL-33) is highly expressed in barrier sites, acting via the suppression of
tumorigenicity 2 receptor (ST2). IL-33/ST2 axis has long been known to play a pivotal role in …

Regulatory T (Treg) cells and cancer-associated fibroblasts (CAFs) jointly promote tumor
immune tolerance and tumorigenesis. The molecular apparatus that drives Treg cell and …

Biomaterial implants are an established part of medical practice, encompassing a broad
range of devices that widely differ in function and structural composition. However, one …

Nonalcoholic steatohepatitis (NASH) affects 3%‐5% of the US population, having severe
clinical complications to the development of fibrosis and end‐stage liver diseases, such as …

IL-33, a nuclear alarmin released during cell death, exerts context-specific effects on
adaptive and innate immune cells, eliciting potent inflammatory responses. We screened …

Cardiac fibrosis is a significant global health problem associated with nearly all forms of
heart disease. In the heart interstitial fibrosis may be reparative, replacing areas damaged …

The use of molecular biomarkers for the early detection of heart disease, before their onset
of symptoms, is an attractive novel approach. Ideal molecular biomarkers, those that are …

Endometriosis is a debilitating condition that is categorized by the abnormal growth of
endometrial tissue outside the uterus. Although the pathogenesis of this disease remains …