The global burden of antimicrobial resistance–urinary tract infections

S Von Vietinghoff, O Shevchuk… - Nephrology Dialysis …, 2024 - academic.oup.com
Antimicrobial resistance (AMR) has emerged as a significant global healthcare problem.
Antibiotic use has accelerated the physiologic process of AMR, particularly in Gram-negative …

Improving antimicrobial use through better diagnosis: the relationship between diagnostic stewardship and antimicrobial stewardship

TSN Ku, M Al Mohajer, JA Newton… - Infection Control & …, 2023 - cambridge.org
Antimicrobial stewardship programs (ASPs) exist to optimize antibiotic use, reduce selection
for antimicrobial-resistant microorganisms, and improve patient outcomes. Rapid and …

When antimicrobial stewardship begins with microbiological test requests: The case of asymptomatic bacteriuria

H Imlay, A Thorpe, VM Vaughn - Current Opinion in Infectious …, 2024 - journals.lww.com
Diagnostic stewardship can decrease unnecessary antibiotics and inappropriate diagnosis
of UTI with multifaceted interventions most likely to be effective. Remaining questions …

Stewardship prompts to improve antibiotic selection for urinary tract infection: the INSPIRE randomized clinical trial

SK Gohil, E Septimus, K Kleinman, N Varma, TR Avery… - JAMA, 2024 - jamanetwork.com
Importance Urinary tract infection (UTI) is the second most common infection leading to
hospitalization and is often associated with gram-negative multidrug-resistant organisms …

Development of patient safety measures to identify inappropriate diagnosis of common infections

AT White, VM Vaughn, LA Petty… - Clinical Infectious …, 2024 - academic.oup.com
Background Inappropriate diagnosis of infections results in antibiotic overuse and may delay
diagnosis of underlying conditions. Here we describe the development and characteristics of …

Increasing evidence that diagnostic stewardship may improve antibiotic use

DJ Morgan, S Leekha, KC Claeys - JAMA Internal Medicine, 2023 - jamanetwork.com
Asymptomatic bacteriuria (ASB) is a diagnosis created to counter the persistent belief that a
positive urine culture equals urinary tract infection (UTI), which equals antibiotics. 1 Positive …

Performance of Urinalysis Parameters in Predicting Urinary Tract Infection: Does One Size Fit all?

SD Advani, R North, NA Turner… - Clinical Infectious …, 2024 - academic.oup.com
In a multi-hospital cohort study of 3392 patients, positive urinalysis parameters had poor
positive predictive value for diagnosing urinary tract infection (UTI). Combined urinalysis …

BLADDER score: evaluating a tool to support urinary diagnostic and antibiotic stewardship in hospitalized adults

BJ Langford, S Amoah, J Hansen, L Hudd… - Infection Control & …, 2024 - cambridge.org
Objective: Antibiotic overuse for asymptomatic bacteriuria is common in older adults and can
lead to harmful outcomes including antimicrobial resistance. Our objective was to evaluate …

Protocol for a parallel cluster randomized trial of a participatory tailored approach to reduce overuse of antibiotics at hospital discharge: the ROAD home trial

JE Szymczak, LA Petty, TN Gandhi, RA Neetz… - Implementation …, 2024 - Springer
Background Antibiotic overuse at hospital discharge is common, costly, and harmful. While
discharge-specific antibiotic stewardship interventions are effective, they are resource …

[HTML][HTML] Sustainability in healthcare by reducing low-value imaging–A narrative review

E Kjelle, IØ Brandsæter, ER Andersen, B Hofmann - Radiography, 2024 - Elsevier
Objectives This narrative review aims to present the concept of value in imaging and explore
why we conduct low-value procedures, how to reduce this wasteful use, and what we could …