Bioactive inorganic nanomaterials for cancer theranostics

Z Pei, H Lei, L Cheng - Chemical Society Reviews, 2023 - pubs.rsc.org
Bioactive materials are a special class of biomaterials that can react in vivo to induce a
biological response or regulate biological functions, thus achieving a better curative effect …

[HTML][HTML] The PTGS2/COX2-PGE2 signaling cascade in inflammation: Pro or anti? A case study with type 1 diabetes mellitus

E Martín-Vázquez, N Cobo-Vuilleumier… - … journal of biological …, 2023 - ncbi.nlm.nih.gov
Prostaglandins are lipid mediators involved in physiological processes, such as constriction
or dilation of blood vessels, but also pathophysiological processes, which include …

Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn's disease

J Li, AJ Simmons, CV Hawkins, S Chiron… - Nature …, 2024 - nature.com
Crohn's disease (CD) is a complex chronic inflammatory disorder with both gastrointestinal
and extra-intestinal manifestations associated immune dysregulation. Analyzing 202,359 …

FOXO1 orchestrates the intestinal homeostasis via neuronal signaling in group 3 innate lymphoid cells

F Shao, Z Liu, Q Wei, D Yu, M Zhao, X Zhang… - Journal of Experimental …, 2023 - rupress.org
The neuro-immune regulation is associated with homeostasis of the intestine. Intestinal
group 3 innate lymphoid cells (ILC3s) are tissue-resident lymphocytes whose functions are …

Regulation of systemic metabolism by tissue-resident immune cell circuits

JH Li, MR Hepworth, TE O'Sullivan - Immunity, 2023 - cell.com
Recent studies have demonstrated that tissue homeostasis and metabolic function are
dependent on distinct tissue-resident immune cells that form functional cell circuits with …

Metabolic control of innate lymphoid cells in health and disease

L Zhou, Q Lin, GF Sonnenberg - Nature metabolism, 2022 - nature.com
Innate lymphoid cells (ILCs) are a family of predominantly tissue-resident lymphocytes that
critically orchestrate immunity, inflammation, tolerance and repair at barrier surfaces of the …

Group 3 innate lymphoid cells in intestinal health and disease

V Horn, GF Sonnenberg - Nature Reviews Gastroenterology & …, 2024 - nature.com
The gastrointestinal tract is an immunologically rich organ, containing complex cell networks
and dense lymphoid structures that safeguard this large absorptive barrier from pathogens …

Innate lymphoid cells: More than just immune cells

L Xiong, SL Nutt, C Seillet - Frontiers in Immunology, 2022 - frontiersin.org
Since their discovery, innate lymphoid cells (ILCs) have been described as the innate
counterpart of the T cells. Indeed, ILCs and T cells share many features including their …

Identification of HBEGF+ fibroblasts in the remission of rheumatoid arthritis by integrating single-cell RNA sequencing datasets and bulk RNA sequencing datasets

N Chen, B Fan, Z He, X Yu, J Wang - Arthritis research & therapy, 2022 - Springer
Background Fibroblasts are important structural cells in synovium and play key roles in
maintaining the synovial homeostasis. By single-cell RNA sequencing (scRNA-seq) …

Transcriptional control of ILC identity

AA Korchagina, SA Shein, E Koroleva… - Frontiers in …, 2023 - frontiersin.org
Innate lymphoid cells (ILCs) are heterogeneous innate immune cells which participate in
host defense, mucosal repair and immunopathology by producing effector cytokines …