Apical constriction is a cell shape change that promotes tissue remodeling in a variety of
homeostatic and developmental contexts, including gastrulation in many organisms and …

Many genes and molecules that drive tissue patterning during organogenesis and tissue
regeneration have been discovered. Yet, we still lack a full understanding of how these …

Apical constriction facilitates epithelial sheet bending and invagination during
morphogenesis,. Apical constriction is conventionally thought to be driven by the continuous …

Tissue morphogenesis arises from coordinated changes in cell shape driven by actomyosin
contractions. Patterns of gene expression regionalize cell behaviours by controlling …

Myosins constitute a large superfamily of actin-dependent molecular motors. Phylogenetic
analysis currently places myosins into 15 classes. The conventional myosins which form …

Background: Simple epithelia encase developing embryos and organs. Although these
epithelia consist of only one or two layers of cells, they must provide tight barriers for the …

Biologists have long recognized that dramatic bending of a cell sheet may be driven by even
modest shrinking of the apical sides of cells. Cell shape changes and tissue movements like …

The molecular and cellular bases of cell shape change and movement during
morphogenesis and wound healing are of intense interest and are only beginning to be …

Epithelial–mesenchymal transitions (EMTs) are an important mechanism for reorganizing
germ layers and tissues during embryonic development. They have both a morphogenic …

Development, homeostasis and regeneration of tissues result from a complex combination
of genetics and mechanics, and progresses in the former have been quicker than in the …