The biological applications of DNA nanomaterials: current challenges and future directions

W Ma, Y Zhan, Y Zhang, C Mao, X Xie… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

DNA nanotechnology approaches for microRNA detection and diagnosis

AR Chandrasekaran, JA Punnoose, L Zhou… - Nucleic acids …, 2019 - academic.oup.com
MicroRNAs are involved in the crucial processes of development and diseases and have
emerged as a new class of biomarkers. The field of DNA nanotechnology has shown great …

DNA origami-based protein networks: from basic construction to emerging applications

G Kong, M Xiong, L Liu, L Hu, HM Meng, G Ke… - Chemical Society …, 2021 - pubs.rsc.org
Natural living systems are driven by delicate protein networks whose functions are precisely
controlled by many parameters, such as number, distance, orientation, and position …

Mastering the tools: natural versus artificial vesicles in nanomedicine

L Leggio, G Arrabito, V Ferrara… - Advanced …, 2020 - Wiley Online Library
Naturally occurring extracellular vesicles and artificially made vesicles represent important
tools in nanomedicine for the efficient delivery of biomolecules and drugs. Since its first …

Structural DNA nanotechnology at the nexus of next-generation bio-applications: challenges and perspectives

S Kosara, R Singh, D Bhatia - Nanoscale Advances, 2024 - pubs.rsc.org
DNA nanotechnology has significantly progressed in the last four decades, creating nucleic
acid structures widely used in various biological applications. The structural flexibility …

Non-origami DNA for functional nanostructures: From structural control to advanced applications

L Zhang, X Ma, G Wang, X Liang, H Mitomo, A Pike… - Nano Today, 2021 - Elsevier
The revolutionary idea that DNA can play a non-biological role in a material world has
indeed become today's reality. Although much attentions have recently been paid to …

DNA nanotechnology: A recent advancement in the monitoring of microcystin-LR

T Suo, M Sohail, S Xie, B Li, Y Chen, L Zhang… - Journal of Hazardous …, 2021 - Elsevier
Abstract The Microcystin-Leucine-Arginine (MC-LR) is the most toxic and widely distributed
microcystin, which originates from cyanobacteria produced by water eutrophication. The MC …

Self-assembled DNA nanomaterials with highly programmed structures and functions

Z Li, J Wang, Y Li, X Liu, Q Yuan - Materials Chemistry Frontiers, 2018 - pubs.rsc.org
Long admired as the repository of genetic information, DNA has more recently been
exploited as a powerful material for self-assembly. Taking advantage of the specificity and …

When nanoworlds collide: implementing DNA amplification, nanoparticles, molecules, and FRET into a single microRNA biosensor

J Xu, X Qiu, N Hildebrandt - Nano Letters, 2021 - ACS Publications
Isothermal nucleic acid amplification strategies have been combined with nanotechnology
for advanced biosensing, material design, and biomedical applications. However, merging …

Integrated DNA triangular prism nanomachines for two-stage dynamic recognizing and bio-imaging from surface to the inside of living cells

S Xu, T Wu, N Ren, J Li, Y Zhang, H Wang, H Liu… - Biosensors and …, 2022 - Elsevier
The identification and detection of biomarkers in cancer cells play an essential role in the
early detection of diseases, especially the detection of dual-biomarker. However, one of the …