Parasitic diseases, including malaria, leishmaniasis, and trypanosomiasis, affect billions of people and are responsible for almost 500,000 deaths/year. In particular, leishmaniasis, a …
MNC Soeiro, AP Dantas, A Daliry… - Memórias do Instituto …, 2009 - SciELO Brasil
Chagas disease, which is caused by the intracellular parasite Trypanosoma cruzi, is a neglected illness with 12-14 million reported cases in endemic geographic regions of Latin …
DGJ Batista, MM Batista, GM Oliveira… - Antimicrobial Agents …, 2010 - Am Soc Microbiol
Chagas' disease, a neglected tropical illness for which current therapy is unsatisfactory, is caused by the intracellular parasite Trypanosoma cruzi. The goal of this work is to …
RM Katona, AW Knight, M Maguire, CR Bryan… - Science of The Total …, 2023 - Elsevier
Measured salt compositions in dust collected over roughly the last decade from surfaces of in-service stainless-steel alloys at four locations around the United States are presented …
MZ Wang, X Zhu, A Srivastava, Q Liu… - Antimicrobial Agents …, 2010 - Am Soc Microbiol
Arylimidamides (AIAs) represent a new class of molecules that exhibit potent antileishmanial activity (50% inhibitory concentration [IC50],< 1 μM) against both Leishmania donovani …
CS Maria de Nazaré, SL de Castro - The Open Medicinal …, 2011 - ncbi.nlm.nih.gov
Chagas disease (CD), caused by the intracellular protozoan Trypanosoma cruzi, is a parasitic illness endemic in Latin America. In the centennial after CD discovery by Carlos …
E van den Bogaart, GJ Schoone… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Critical to the search for new anti-leishmanial drugs is the availability of high-throughput screening (HTS) methods to test chemical compounds against the relevant stage for …
K Maji, M Abbasi, D Podder, R Datta… - ChemistrySelect, 2018 - Wiley Online Library
The dipeptides 1–4 with a triazole containing synthetic amino acid and Leu/Phe/Val/Gly have been designed and synthesized as a potent antileishmanial agent. The 1‐(2‐Amino …
A Daliry, MQ Pires, CF Silva, RS Pacheco… - Antimicrobial agents …, 2011 - Am Soc Microbiol
Due to limited efficacy and considerable toxicity, the therapy for Chagas' disease is far from being ideal, and thus new compounds are desirable. Diamidines and related compounds …