Most therapeutic agents suffer from poor solubility, rapid clearance from the blood stream, a
lack of targeting, and often poor translocation ability across cell membranes. Drug/gene …

Within the field of gene therapy, there is a considerable need for the development of non-
viral vectors that are able to compete with the efficiency obtained by viral vectors, while …

The cellular uptake of nanoparticles (NPs) has drawn significant attention due to their great
importance and potential in drug delivery, bioimaging, and specific targeting. Here, we …

The cell uptake rate of nanoparticles (NPs) coated with mixed hydrophilic/hydrophobic
ligands is known to be strongly influenced by the ligand pattern on the nanoparticle surface …

Although a variety of non-viral gene delivery vectors has been synthesized and used for
gene delivery purposes, well-defined glycopolymer-based gene delivery carriers is not well …

When nanoparticles interact with their environment, the nature of that interaction is governed
largely by the properties of its outermost surface layer. Here, we exploit the exceptional …

In this work we study the titration behavior of weak polyelectrolytes by computer simulations.
We analyze the local pH near the chains at various conditions and provide molecular-level …

This article reviews current experimental observations and theoretical calculations devoted
towards understanding micro-phase separation in charged block copolymer systems. We …

A series of glycopolymers composed of 2-deoxy-2-methacrylamido glucopyranose (MAG)
and the primary amine-containing N-(2-aminoethyl) methacrylamide (AEMA) were …

Mechanochemistry can lead to the degradation of the properties of covalent
macromolecules. In recent years, numerous functional materials have been developed …