Cancer is a heavy burden for humans across the world with high morbidity and mortality.
Transcription factors including sex determining region Y (SRY)-related high-mobility group …

SOX4 is an essential developmental transcription factor that regulates stemness,
differentiation, progenitor development, and multiple developmental pathways including …

Gene expression profiling has uncovered the transcription factor Sox4 with upregulated
activity during TGF-β-induced epithelial-mesenchymal transition (EMT) in normal and …

Epithelial–mesenchymal transition (EMT) is a developmental program, which is associated
with breast cancer progression and metastasis. Here, we report that ectopic overexpression …

Abstract Development and progression of cancer are mediated by alterations in
transcriptional networks, resulting in a disturbed balance between the activity of oncogenes …

The prognostic role of the transcription factor SOX11 in mantle cell lymphoma (MCL) is
controversial. We investigated prognostic markers in a population-based cohort of 186 MCL …

Background & Aims Modulation of microRNA expression is a potential treatment for
hepatocellular carcinoma (HCC). Therefore, the epigenetically regulated microRNA-449 …

Despite investment in toxicogenomics, nonclinical safety studies are still used to predict
clinical liabilities for new drug candidates. Network-based approaches for genomic analysis …

Hepatocellular carcinoma (HCC) is one of the most common public health challenges,
worldwide. Because of molecular complexity and tumor heterogeneity, there are no effective …

Angiotensin II (Ang II)-mediated vascular smooth muscle cell dysfunction plays a critical role
in cardiovascular diseases. However, the role of microRNAs (miRNAs) in this process is …