Sex differences in blood pressure regulation and hypertension: renal, hemodynamic, and hormonal mechanisms

ER Drury, J Wu, JC Gigliotti, TH Le - Physiological Reviews, 2024 - journals.physiology.org
The teleology of sex differences has been argued since at least as early as Aristotle's
controversial Generation of Animals more than 300 years BC, which reflects the sex bias of …

Summary of known genetic and epigenetic modification contributed to hypertension

TM Pratamawati, I Alwi… - International Journal of …, 2023 - Wiley Online Library
Hypertension is a multifactorial disease due to a complex interaction among genetic,
epigenetic, and environmental factors. Characterized by raised blood pressure (BP), it is …

Cullin 3 and blood pressure regulation: Insights from familial hyperkalemic hypertension

Y Maeoka, RJ Cornelius, JA McCormick - Hypertension, 2023 - Am Heart Assoc
The study of rare monogenic forms of hypertension has led to the elucidation of important
physiological pathways controlling blood pressure. Mutations in several genes cause …

Effect of blood flow restriction training on health promotion in middle-aged and elderly women: a systematic review and meta-analysis

M Feng, J Li, J Zhao, X Pan, M Wang, Q Han - Frontiers in Physiology, 2024 - frontiersin.org
Background: Physical activities play an important role in alleviating the aging problem and
improving the physical fitness of middle-aged and elderly people. Blood flow restriction …

Insights into the diverse mechanisms and effects of variant CUL3-induced familial hyperkalemic hypertension

P Sharma, HE Chatrathi - Cell Communication and Signaling, 2023 - Springer
Familial hyperkalemic hypertension (FHHt), also known as Pseudohypoaldosteronism type II
(PHAII) or Gordon syndrome is a rare Mendelian disease classically characterized by …

Cullin 3/with No Lysine [K] Kinase/Ste20/SPS-Related Proline Alanine Rich Kinase Signaling: Impact on NaCl Cotransporter Activity in BP Regulation

K Omage, JA McCormick - Kidney360, 2024 - journals.lww.com
The sodium chloride cotransporter (NCC) fine-tunes Na+ balance and indirectly affects the
homeostasis of other ions including K+, Mg 2+, and Ca 2+. Owing to its effects on Na+ …

Cullin3/WNK/SPAK signaling: impact on NaCl cotransporter activity in blood pressure regulation

K Omage, JA McCormick - Kidney360, 2024 - journals.lww.com
The sodium chloride co-transporter (NCC) fine-tunes Na+ balance and indirectly affects the
homeostasis of other ions including K+, Mg 2+ and Ca 2+. Due to its effects on Na+ balance …

Paradigm shift in hyperglycemic glomerular hyperfiltration: blunted tubuloglomerular feedback or preglomerular vasodilation?

J Wu - Hypertension, 2023 - Am Heart Assoc
Chronic kidney disease affects≈ 15% of US adults or 37 million people, resulting in $87
billion health care cost annually. 1 Diabetes, obesity, and hypertension are leading risk …

Mechanisms of Xuefu Zhuyu Tang in the Treatment of Diabetic Erectile Dysfunction in Rats Through the Regulation of Vascular Endothelial Function by CaSR/PLC …

X Li, M Zhang, J Feng, J Wang… - American Journal of …, 2024 - journals.sagepub.com
Xuefu zhuyu Tang (XFZYT) is a classic formula used for promoting blood circulation and
resolving blood stasis in Traditional Chinese Medicine. Clinical data have indicated that …

Uncovering the Complexities of Salt Sensitivity

DM Pollock - Function, 2022 - academic.oup.com
Historically speaking, the dangers of chronic high salt diets in Western culture is a relatively
modern phenomenon. Throughout human history, empires were built and wars fought over …