Risk factors for severe and critically ill COVID‐19 patients: a review

Y Gao, M Ding, X Dong, J Zhang, A Kursat Azkur… - Allergy, 2021 - Wiley Online Library
The pandemic of coronavirus disease 2019 (COVID‐19), caused by the severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused an unprecedented global …

Current status of potential therapeutic candidates for the COVID-19 crisis

J Zhang, B Xie, K Hashimoto - Brain, behavior, and immunity, 2020 - Elsevier
Abstract As of April 15, 2020, the ongoing coronavirus disease 2019 (COVID-2019)
pandemic has swept through 213 countries and infected more than 1,870,000 individuals …

Effect of vitamin C infusion on organ failure and biomarkers of inflammation and vascular injury in patients with sepsis and severe acute respiratory failure: the CITRIS …

JD Truwit, RD Hite, PE Morris, C DeWilde, A Priday… - Jama, 2019 - jamanetwork.com
Importance Experimental data suggest that intravenous vitamin C may attenuate
inflammation and vascular injury associated with sepsis and acute respiratory distress …

Pilot trial of high-dose vitamin C in critically ill COVID-19 patients

J Zhang, X Rao, Y Li, Y Zhu, F Liu, G Guo, G Luo… - Annals of intensive …, 2021 - Springer
Background Few specific medications have been proven effective for the treatment of
patients with severe coronavirus disease 2019 (COVID-19). Here, we tested whether high …

[HTML][HTML] Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression

G Schönrich, MJ Raftery, Y Samstag - Advances in biological regulation, 2020 - Elsevier
Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …

[HTML][HTML] Vitamin C and immune function

AC Carr, S Maggini - Nutrients, 2017 - mdpi.com
Vitamin C is an essential micronutrient for humans, with pleiotropic functions related to its
ability to donate electrons. It is a potent antioxidant and a cofactor for a family of biosynthetic …

Effect of vitamin C, hydrocortisone, and thiamine vs hydrocortisone alone on time alive and free of vasopressor support among patients with septic shock: the …

T Fujii, N Luethi, PJ Young, DR Frei, GM Eastwood… - Jama, 2020 - jamanetwork.com
Importance It is unclear whether vitamin C, hydrocortisone, and thiamine are more effective
than hydrocortisone alone in expediting resolution of septic shock. Objective To determine …

Could vitamins help in the fight against COVID-19?

TH Jovic, SR Ali, N Ibrahim, ZM Jessop, SP Tarassoli… - Nutrients, 2020 - mdpi.com
There are limited proven therapeutic options for the prevention and treatment of COVID-19.
The role of vitamin and mineral supplementation or “immunonutrition” has previously been …

Intravenous high-dose vitamin C for the treatment of severe COVID-19: study protocol for a multicentre randomised controlled trial

F Liu, Y Zhu, J Zhang, Y Li, Z Peng - BMJ open, 2020 - bmjopen.bmj.com
Introduction The rapid worldwide spread of COVID-19 has caused a global health crisis. To
date, symptomatic supportive care has been the most common treatment. It has been …

Vitamin C and COVID-19 treatment: A systematic review and meta-analysis of randomized controlled trials

D Rawat, A Roy, S Maitra, A Gulati, P Khanna… - Diabetes & Metabolic …, 2021 - Elsevier
Background and aims Vitamin C has been used as an anti-oxidant in various diseases
including viral illnesses like coronavirus disease (COVID-19). Methods Meta-analysis of …