Insomnia and obstructive sleep apnea (OSA) commonly co-occur. Approximately 30–50% of
patients with OSA report clinically significant insomnia symptoms, and 30–40% of patients …

Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

Background Increased mortality has been reported in people with insomnia and in those
with obstructive sleep apnoea (OSA). However, these conditions commonly co-occur and …

Introduction The last two decades have witnessed a rapid increase in the knowledge about
the role of the orexin system, particularly in the regulation of wakefulness and arousal. Dual …

Comorbid insomnia and sleep apnoea (COMISA) is a highly prevalent and debilitating sleep
disorder. Cognitive behavioural therapy for insomnia (CBTi) may be an appropriate …

Orexin is a neurotransmitter produced by a small group of hypothalamic neurons. Besides its
well-known role in the regulation of the sleep-wake cycle, the orexin system was shown to …

Introduction Insomnia and obstructive sleep apnoea (OSA) are the two most prevalent sleep
disorders, and frequently co-occur (COMISA) in sleep clinic samples. However, few studies …

Purpose Insomnia symptoms and sleep apnea frequently co-occur and are associated with
worse sleep, daytime function, mental health and quality of life, compared to either insomnia …

Introduction Estimating insomnia prevalence in epidemiological studies is hampered by
variability in definitions and interpretation of criteria. We addressed the absence of a …

Insomnia and obstructive sleep apnea (OSA) are the two most common sleep disorders and
frequently co-occur. 1 The co-occurrence of insomnia and OSA in the same person was first …