It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was
discovered. EBV has subsequently been found to be associated with a diverse range of …

Persistent infection by EBV is explained by the germinal center model (GCM) which provides
a satisfying and currently the only explanation for EBVs disparate biology. Since the GCM …

Nuclear Factor-kappa B (NF-κB) is a transcription factor family that regulates a large number
of genes that are involved in important physiological processes, including survival …

Epstein–Barr virus (EBV) was discovered 40 years ago from examining electron
micrographs of cells cultured from Burkitt's lymphoma, a childhood tumour that is common in …

EBV was the first human virus to be directly implicated in carcinogenesis. It infects> 90% of
the world's population. Although most humans coexist with the virus without serious …

Abstract In vitro, Epstein-Barr virus (EBV) will infect any resting B cell, driving it out of the
resting state to become an activated proliferating lymphoblast. Paradoxically, EBV persists in …

EBV is a prevalent virus, infecting> 90% of the world's population. This is an oncogenic virus
that causes~ 200,000 cancer-related deaths annually. It is, in addition, a significant …

Since the discovery in 1964 of the Epstein–Barr virus (EBV) in African Burkitt lymphoma, this
virus has been associated with a remarkably diverse range of cancer types. Because EBV …

Viruses, as obligate intracellular parasites, are the pathogens that have the most intimate
relationship with their host, and as such, their genomes have been shaped directly by …

The inhibitor of apoptosis protein family has been characterized over the past 5 years,
initially in baculovirus and more recently in metazoans. The IAPs are a widely expressed …