The epithelial-mesenchymal transition (EMT) represents a biological program during which
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …

The Warburg effect is a phenomenon in which cancer cells rely primarily on glycolysis rather
than oxidative phosphorylation, even in the presence of oxygen. Although evidence of its …

Glioblastoma multiforme (GBM) remains the top challenge to radiotherapy with only 25%
one-year survival after diagnosis. Here, we reveal that co-enhancement of mitochondrial …

Cancers are generally recognized as the leading cause of death and a predominant barrier
to prolonging life expectancy in both developed and developing countries. Emodin is a …

Metabolic rearrangement is a marker of cancer that has been widely studied in recent years.
One of the major metabolic characteristics of tumor cells is the high levels of glycolysis, even …

Glioblastoma (GBM), the most aggressive brain tumor, is associated with a median survival
at diagnosis of 16–20 months and limited treatment options. The key hallmark of GBM is …

Glioblastoma (GBM) is the most malignant primary brain tumor. The current standard
approach in GBM is surgery, followed by treatment with radiation and temozolomide (TMZ); …

Abstract Background Glioblastoma Multiforme (GBM) is a malignant primary brain tumor in
which the standard treatment, ionizing radiation (IR), achieves a median survival of about 15 …

Glioblastoma (GBM) currently has a dismal prognosis. GBM cells that survive radiotherapy
contribute to tumor progression and recurrence with metabolic advantages. Here, we show …

Background There are few effective medications for treating colorectal cancer and liver
metastases (CRLM). The interactions among glycolysis, epithelial-mesenchymal transition …