[HTML][HTML] Structure activity relationship and target prediction for ABX464 analogues in Caenorhabditis elegans
Global challenges with treatment failures and/or widespread resistance in parasitic worms
against commercially available anthelmintics lend impetus to the development of new …
against commercially available anthelmintics lend impetus to the development of new …
Biocontrol activity and potential mechanism of Bacillus cereus G5 against Meloidogyne graminicola
S Ye, S Zhou, Y Ma, J Yang, X Shi, R Zhang… - Pesticide Biochemistry …, 2024 - Elsevier
Root-knot nematodes (Meloidogyne spp.) are highly destructive pests that cause significant
yield losses annually. Biological control of nematodes has emerged as a potential …
yield losses annually. Biological control of nematodes has emerged as a potential …
Evaluating alternative compounds for strongyloidiasis therapy: Novel insights from larval migration inhibition test
M Cambra-Pellejà, E Valderas-García… - PLoS neglected …, 2024 - journals.plos.org
Strongyloidiasis is a neglected tropical disease estimated to affect more than 600 million
people worldwide. Recently, the World Health Organization road map on neglected tropical …
people worldwide. Recently, the World Health Organization road map on neglected tropical …
[HTML][HTML] Comparative structure activity and target exploration of 1, 2-diphenylethynes in Haemonchus contortus and Caenorhabditis elegans
Infections and diseases caused by parasitic nematodes have a major adverse impact on the
health and productivity of animals and humans worldwide. The control of these parasites …
health and productivity of animals and humans worldwide. The control of these parasites …
[HTML][HTML] Structure-activity relationship and target investigation of 2-aryl quinolines with nematocidal activity
Within the context of our anthelmintic discovery program, we recently identified and
evaluated a quinoline derivative, called ABX464 or obefazimod, as a nematocidal …
evaluated a quinoline derivative, called ABX464 or obefazimod, as a nematocidal …
Mechanisms of Antimicrobial Agent Cetylpyridinium Chloride Mitochondrial Toxicity in Rodent and Primary Human Cells: Super-resolution Microscopy Reveals …
SR Weller, JE Burnell, BM Aho, B Obeng, EL Ledue… - bioRxiv, 2022 - biorxiv.org
People are exposed to high concentrations of antibacterial agent cetylpyridinium chloride
(CPC) via personal care and food products, despite little information regarding CPC effects …
(CPC) via personal care and food products, despite little information regarding CPC effects …
[HTML][HTML] Development and validation of an epithelial–mesenchymal transition-related gene signature for predicting prognosis
DH Zhou, QC Du, Z Fu, XY Wang, L Zhou… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Currently, there are many therapeutic methods for lung adenocarcinoma
(LUAD), but the 5-year survival rate is still only 15% at later stages. Epithelial–mesenchymal …
(LUAD), but the 5-year survival rate is still only 15% at later stages. Epithelial–mesenchymal …