Local and systemic mechanisms that control the hair follicle stem cell niche

B Zhang, T Chen - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Hair follicles are essential appendages of the mammalian skin, as hair performs vital
functions of protection, thermoregulation and sensation. Hair follicles harbour exceptional …

Inorganic-based biomaterials for rapid hemostasis and wound healing

Y Zheng, J Wu, Y Zhu, C Wu - Chemical Science, 2023 - pubs.rsc.org
The challenge for the treatment of severe traumas poses an urgent clinical need for the
development of biomaterials to achieve rapid hemostasis and wound healing. In the past …

Psychological stress-induced pathogenesis of alopecia areata: autoimmune and apoptotic pathways

D Ahn, H Kim, B Lee, DH Hahm - International Journal of Molecular …, 2023 - mdpi.com
Alopecia areata (AA) is an autoimmune dermatological disease with multifactorial etiology
and is characterized by reversible hair loss in patches. AA may be closely related to …

Cellular activation pathways and interaction networks in vascularized composite allotransplantation

L Knoedler, S Knoedler, AC Panayi, CAA Lee… - Frontiers in …, 2023 - frontiersin.org
Vascularized composite allotransplantation (VCA) is an evolving field of reconstructive
surgery that has revolutionized the treatment of patients with devastating injuries, including …

Reprograming the immune niche for skin tissue regeneration–from cellular mechanisms to biomaterials applications

R Mu, SC de Souza, Z Liao, L Dong, C Wang - Advanced Drug Delivery …, 2022 - Elsevier
Despite the rapid development of therapeutic approaches for skin repair, chronic wounds
such as diabetic foot ulcers remain an unaddressed problem that affects millions of people …

Unmasking Chemokine‐Inducing Specificity in Oligosaccharide Biomaterial to Promote Hair Growth

X Yin, L Wang, Y Niu, D Xie, Q Zhang, J Xiao… - Advanced …, 2024 - Wiley Online Library
Hair loss affects over 50 million people worldwide with limited therapeutic options. Despite
evidence highlighting the vital role of local immune cells in regulating the life cycle of hair …

[HTML][HTML] Strontium zinc silicate bioceramic composite electrospun fiber membrane for hair follicle regeneration in burn wounds

J Yu, Y Xu, Z Zhang, Z Zeng, D Chen, Z Wei… - Composites Part B …, 2023 - Elsevier
Traditional wound dressings lack the activity to promote hair follicle regeneration during the
treatment of deep burn skin injuries. In this study, a composite electrospun wound dressing …

Skin organoids: a new human model for developmental and translational research

J Lee, KR Koehler - Experimental dermatology, 2021 - Wiley Online Library
Culturing skin cells outside of the body has been a cornerstone of dermatological
investigation for many years; however, human skin equivalent systems typically lack the full …

Hair follicle stem cells as a skin‐organizing signaling center during adult homeostasis

KN Li, T Tumbar - The EMBO Journal, 2021 - embopress.org
Stem cells are the essential source of building blocks for tissue homeostasis and
regeneration. Their behavior is dictated by both cell‐intrinsic cues and extrinsic cues from …

Alarmin cytokines as central regulators of cutaneous immunity

T Hasegawa, T Oka, S Demehri - Frontiers in Immunology, 2022 - frontiersin.org
Skin acts as the primary interface between the body and the environment. The skin immune
system is composed of a complex network of immune cells and factors that provide the first …