Object Transsphenoidal approaches have been used for a century for the resection of
pituitary and other sellar tumors. More recently, the standard endonasal approach has been …

Pituitary tumors are challenging tumors in the sellar region. Surgical approaches to the
pituitary have undergone numerous refinements over the last 100 years. The introduction of …

Table 1-1. Category of evidence (2). Ia Evidence from meta-analysis of randomised
controlled trials Ib Evidence from at least one randomised controlled trial IIa Evidence from …

✓ Initial attempts at transcranial approaches to the pituitary gland in the late 1800s and early
1900s resulted in a mortality rate that was generally considered prohibitive. Schloffer …

OBJECTIVE: The traditional boundaries of the transsphenoidal approach may be expanded
to include the region from the cribriform plate of the anterior cranial base to the inferior clivus …

The endoscopic endonasal transsphenoidal approach has been proposed in the past
decade as a minimally invasive surgical technique for the removal of pituitary tumors. From …

Object The extended transsphenoidal approach is a less invasive method for removing
purely suprasellar lesions compared with traditional transcranial approaches. Most …

OBJECTIVE Pituitary adenomas (PAs) are benign neoplasms that are frequently
encountered during workup for endocrinopathy, headache, or visual loss. Transsphenoidal …

Background: Endoscopic transsphenoidal surgery was developed under a minimally
invasive surgical strategy. This endonasal transsphenoidal endoscopy eliminates a …

Object Because of their size and lateral extension, total removal of nonfunctioning pituitary
adenomas (NFPAs) remains a challenge and postoperative tumor remnants are frequent …