Dengue is the disease caused by 1 of 4 distinct, but closely related dengue viruses (DENV-1–
4) that are transmitted by Aedes spp. mosquito vectors. It is the most common arboviral …

Zika and dengue viruses belong to the Flavivirus genus, a close group of antigenically
related viruses that cause significant arthropod‐transmitted diseases throughout the globe …

For dengue viruses 1 to 4 (DENV1-4), a specific range of antibody titer has been shown to
enhance viral replication in vitro and severe disease in animal models. Although suspected …

The quest for an effective dengue vaccine has culminated in two approved vaccines and
another that has completed phase 3 clinical trials. However, shortcomings exist in each …

Correlates of protection are key for vaccine development against any pathogen. In this paper
we summarize recent information about correlates for vaccines against dengue, Ebola …

Preexisting cross-reactive antibodies have been implicated in both protection and
pathogenesis during subsequent infections with different dengue virus (DENV) serotypes …

This is a selective review of recent publications on dengue clinical features, epidemiology,
pathogenesis, and vaccine development placed in a context of observations made over the …

Rationale for review Dengue is a frequent cause of febrile illness among travellers and has
overtaken malaria as the leading cause of febrile illness for those traveling to Southeast …

Summary The Strategic Advisory Group of Experts (SAGE) on Immunization advises WHO
on global policies for vaccines. In April, 2016, SAGE issued recommendations on the use of …

Antiviral antibodies constitute an important component of the host immune response against
viral infections and serve to neutralize and reduce infectivity of the virus. However, these …